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1. WO1998016315 - LIQUID DISTRIBUTION SYSTEM

Publication Number WO/1998/016315
Publication Date 23.04.1998
International Application No. PCT/US1997/018266
International Filing Date 10.10.1997
Chapter 2 Demand Filed 14.04.1998
IPC
B01F 5/06 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
5Flow mixers; Mixers for falling materials, e.g. solid particles
06Mixers in which the components are pressed together through slits, orifices, or screens
B01J 19/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
B01L 3/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
CPC
B01F 15/0264
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
15Accessories for mixers ; ; Auxiliary operations or auxiliary devices; Parts or details of general application
02Feed or discharge mechanisms
0201Feed mechanisms
0227characterized by the means for feeding the components to the mixer
0264With means for feeding the material with a fractal or tree-type distribution in a surface
B01F 5/0601
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
5Flow mixers
06Mixers in which the components are pressed together through slits, orifices, or screens; ; Static mixers; Mixers of the fractal type
0601Fractal mixers
B01J 19/0046
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
B01J 19/0093
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
0093Microreactors, e.g. miniaturised or microfabricated reactors
B01J 2219/00783
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00781Aspects relating to microreactors
00783Laminate assemblies, i.e. the reactor comprising a stack of plates
B01J 2219/00824
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00781Aspects relating to microreactors
00819Materials of construction
00824Ceramic
Applicants
  • SARNOFF CORPORATION [US]/[US]
Inventors
  • DEMERS, Robert
  • MCBRIDE, Sterling, Eduard
  • KNOEDLER, Christina, Marie
  • AMANTEA, Robert
  • MORONEY, Richard
  • CHERUKURI, Satyam, Choudary
  • O'MARA, Kerry
  • CHIANG, William
Agents
  • SILVERIO, John, V.
Priority Data
08/730,63611.10.1996US
08/744,38607.11.1996US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) LIQUID DISTRIBUTION SYSTEM
(FR) SYSTEME DE DISTRIBUTION DE LIQUIDE
Abstract
(EN)
The liquid distribution system of the invention will be formed of at least three plates, a feedthrough plate (300), a distribution substrate (310) and a reaction cell plate (320). The feedthrough plate (300) is typically bonded to the distribution substrate (310). The reaction cell plate (320) is typically removably fitted to the underside of the distribution substrate (310), or the underside of intermediate plate interposed between the distribution substrate (310) and the reaction cell plate (320). The capillary barriers (370) and sluices created by the second openings (362) or third openings act as a combined valve and pump. The capillary barriers (370) prevent flow to the reaction cell, which flow would be favored by capillary forces, until the first pumps (360) or second pumps (361) provide the extra pressure needed to overcome the capillary barriers (370). Narrowing the sluices can increase the capillary forces favoring flow, thereby reducing the amount of added pressure needed to overcome the capillary barriers (370). The use of the capillary barriers (370) allows flow control to be governed by the first pumps (360) or second pumps (361), which are typically controlled by controller.
(FR)
Le système de distribution de liquide de la présente invention comprend au moins trois plaques, une plaque de traversée (300), un substrat de distribution (310) et une plaque de cellule de réaction (320). La plaque de traversée (300) est généralement fixée au substrat de distribution (310). La plaque de cellule de réaction (320) est généralement fixée de manière amovible sur la face inférieure du substrat de distribution (310), ou sur la face inférieure d'une plaque intermédiaire intercalée entre le substrat de distribution (310) et la plaque de cellule de réaction (320). Les barrières capillaires (370) et les passages formés par les deuxièmes ouvertures (362) ou les troisièmes ouvertures fonctionnent comme une soupape et une pompe combinées. Les barrières capillaires (370) empêchent l'écoulement vers la cellule de réaction (lequel écoulement aurait été autrement stimulé par des forces de capillarité) jusqu'à ce que les premières pompes (360) ou les deuxièmes pompes (361) fournissent la pression supplémentaire nécessaire pour l'emporter sur les barrières capillaires (370). Le rétrécissement des passages peut augmenter la stimulation de l'écoulement par les forces de capillarité et, partant, réduire la pression supplémentaire nécessaire pour l'emporter sur les barrières capillaires (370). La mise en oeuvre des barrières capillaires (370) permet une régulation de l'écoulement par les premières pompes (360) ou les deuxièmes pompes (361), lesquelles sont généralement commandées par un régulateur.
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