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1. (WO1998016222) PREPARATION OF 3-FLUORO OXINDOLE DERIVATIVES

Pub. No.:    WO/1998/016222    International Application No.:    PCT/US1997/015323
Publication Date: Apr 23, 1998 International Filing Date: Oct 7, 1997
IPC: C07C 201/16
C07C 205/56
C07D 209/34
Applicants: BRISTOL-MYERS SQUIBB COMPANY
Inventors: PENDRI, Yadagiri, R.
MARTINEZ, Eduardo, J.
THOTTATHIL, John, K.
HEWAWASAM, Piyasena
Title: PREPARATION OF 3-FLUORO OXINDOLE DERIVATIVES
Abstract:
The present invention relates to novel itermediates of formula (1) wherein the wavy bond (∩ ∩) represents the racemate, the (R)-enantiomer or the (S)-enantiomer; and R is hydrogen, a carboxyl-protecting group or a cation of an addition salt; or solvate thereof; and to the use thereof in a process for the preparation of certain 3-fluoro oxindole derivatives.