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1. (WO1998015289) PROTEINS OF KAPOSI'S SARCOMA ASSOCIATED HERPESVIRUS

Pub. No.:    WO/1998/015289    International Application No.:    PCT/US1997/018216
Publication Date: Apr 16, 1998 International Filing Date: Oct 9, 1997
IPC: C07K 14/03
Applicants: CORNELL RESEARCH FOUNDATION, INC.
Inventors: CESARMAN, Ethel
KNOWLES, Daniel, M.
Title: PROTEINS OF KAPOSI'S SARCOMA ASSOCIATED HERPESVIRUS
Abstract:
The present invention is directed to isolated nucleic acid molecules encoding proteins of Kaposi's sarcoma associated herpesvirus, including an antigenic receptor protein, a G protein coupled receptor, and a cyclin protein. Expression vectors and host cells comprising the nucleic acid molecules are also provided, as well as methods for increasing or decreasing the expression of the KSHV proteins in host cells. DNA oligomers and antibodies specific for the KSHV proteins are provided, each of which can be used to detect the KSHV proteins in a sample. Isolated KSHV proteins are also provided.