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1. (WO1998014593) HUMAN TELOMERASE CATALYTIC SUBUNIT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/014593    International Application No.:    PCT/US1997/017885
Publication Date: 09.04.1998 International Filing Date: 01.10.1997
Chapter 2 Demand Filed:    24.04.1998    
IPC:
A61K 38/00 (2006.01), A61K 39/00 (2006.01), A61K 48/00 (2006.01), C12N 9/12 (2006.01), C12N 15/11 (2006.01)
Applicants: GERON CORPORATION [US/US]; 230 Constitution Drive, Menlo Park, CA 94025 (US) (For All Designated States Except US).
UNIVERSITY TECHNOLOGY CORPORATION [US/US]; Suite 250, 3101 Iris Avenue, Boulder, CO 80301 (US) (For All Designated States Except US).
CECH, Thomas, R. [US/US]; (US) (For US Only).
LINGNER, Joachim [CH/US]; (CH) (For US Only).
NAKAMURA, Toru [JP/US]; (US) (For US Only).
CHAPMAN, Karen, B. [US/US]; (US) (For US Only).
MORIN, Gregg, B. [US/US]; (US) (For US Only).
HARLEY, Calvin, B. [CA/US]; (US) (For US Only).
ANDREWS, William, H. [US/US]; (US) (For US Only)
Inventors: CECH, Thomas, R.; (US).
LINGNER, Joachim; (CH).
NAKAMURA, Toru; (US).
CHAPMAN, Karen, B.; (US).
MORIN, Gregg, B.; (US).
HARLEY, Calvin, B.; (US).
ANDREWS, William, H.; (US)
Agent: APPLE, Randolph, T.; Townsend and Townsend and Crew LLP, 8th floor, Two Embarcadero Center, San Francisco, CA 94111-3834 (US)
Priority Data:
08/724,643 01.10.1996 US
08/844,419 18.04.1997 US
08/846,017 25.04.1997 US
08/851,843 06.05.1997 US
08/854,050 09.05.1997 US
08/911,312 14.08.1997 US
08/912,951 14.08.1997 US
08/915,503 14.08.1997 US
Title (EN) HUMAN TELOMERASE CATALYTIC SUBUNIT
(FR) SOUS-UNITE CATALYTIQUE DE LA TELOMERASE D'ORIGINE HUMAINE
Abstract: front page image
(EN)The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for changing the proliferative capacity of cells and organisms, and for identification and screening of compounds and treatments useful for treatment of diseases such as cancers.
(FR)La présente invention se rapporte à des compositions et à des procédés relatifs à la transcriptase inverse de la télomérase humaine (hTRT $i(human telomerase reverse transcriptase)), la sous-unité protéique catalytique de la télomérase d'origine humaine. Les polynucléotides et les polypeptides de la présente invention s'avèrent utiles s'agissant du diagnostic, du pronostic et du traitement de certaines maladies humaines, ils servent à modifier la capacité de prolifération de cellules et d'organismes, et à identifier et à analyser des composés et des traitements adaptés à des maladies telles que les cancers.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)