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Machine translation
1. (WO1998014197) METHOD OF INHIBITING SMOOTH MUSCLE CELL PROLIFERATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/014197    International Application No.:    PCT/US1997/017526
Publication Date: 09.04.1998 International Filing Date: 03.10.1997
Chapter 2 Demand Filed:    30.04.1998    
IPC:
A61K 38/00 (2006.01), A61K 38/45 (2006.01), A61K 48/00 (2006.01), C12N 9/12 (2006.01)
Applicants: DUKE UNIVERSITY [US/US]; 230 North Building, Research Drive, Box 90083, Durham, NC 27708-0083 (US)
Inventors: KOCH, Walter, J.; (US).
LEFKOWITZ, Robert, J.; (US).
HAGEN, Per-Otto; (US)
Agent: WILSON, Mary, J.; Nixon & Vanderhye, P.C., Suite 800, 1100 North Glebe Road, Arlington, VA 22201-4714 (US)
Priority Data:
60/027,775 04.10.1996 US
Title (EN) METHOD OF INHIBITING SMOOTH MUSCLE CELL PROLIFERATION
(FR) PROCEDE POUR INHIBER LA PROLIFERATION DE CELLULES DE MUSCLES LISSES
Abstract: front page image
(EN)The present invention relates, in general, to vascular smooth muscle proliferation and, in particular, to a method of inhibiting arterial and venous smooth muscle proliferation resulting, for example, from arterial injury or vein grafting. The invention also relates to an expression construct encoding a G$g(b)$g(g) inhibitor suitable for use in such a method.
(FR)La présente invention se rapporte, de manière générale, à la prolifération des cellules des muscles vasculaires lisses, à un procédé visant à inhiber la prolifération des muscles lisses veineux et artériels se manifestant, par exemple, à la suite d'une blessure artérielle ou d'une greffe de veine. L'invention se rapporte également à un produit d'expression recombiné codant un inhibiteur de G$g(b)$g(g) adapté à la mise en oeuvre dudit procédé.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)