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1. (WO1998013499) PACKAGING CELL LINES FOR USE IN FACILITATING THE DEVELOPMENT OF HIGH-CAPACITY ADENOVIRAL VECTORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/013499    International Application No.:    PCT/EP1997/005251
Publication Date: 02.04.1998 International Filing Date: 24.09.1997
Chapter 2 Demand Filed:    21.04.1998    
IPC:
A61K 48/00 (2006.01), C07K 14/075 (2006.01), C12N 5/10 (2006.01), C12N 7/00 (2006.01), C12N 15/861 (2006.01)
Applicants: NOVARTIS AG [CH/CH]; Schwarzwaldallee 215, CH-4058 Basel (CH) (For All Designated States Except US).
THE SCRIPPS RESEARCH INSTITUTE [US/US]; 10550 North Torrey Pines Road, La Jolla, CA 92037 (US) (For All Designated States Except US).
NEMEROW, Glen, R. [US/US]; (US) (For US Only).
VON SEGGERN, Daniel, J. [US/US]; (US) (For US Only)
Inventors: NEMEROW, Glen, R.; (US).
VON SEGGERN, Daniel, J.; (US)
Agent: ROTH, Bernhard, M.; Novartis AG, Patent- und Markenabteilung, Lichtstrasse 35, CH-4002 Basel (CH)
Priority Data:
08/719,806 25.09.1996 US
Title (EN) PACKAGING CELL LINES FOR USE IN FACILITATING THE DEVELOPMENT OF HIGH-CAPACITY ADENOVIRAL VECTORS
(FR) LIGNEES CELLULAIRES D'EMBALLAGE PERMETTANT DE FACILITER LE DEVELOPPEMENT DE VECTEURS ADENOVIRAUX D'UNE GRANDE CAPACITE
Abstract: front page image
(EN)The present invention relates to gene therapy, especially to adenovirus-based gene therapy, and related cell lines and compositions. In particular, novel packaging cell lines are disclosed, for use in facilitating the development of high-capacity vectors. The invention also discloses a variety of high-capacity adenovirus vectors and related compositions and kits including the disclosed cell lines and vectors. Finally, the invention discloses methods of preparing and using the disclosed vectors, cell lines and kits.
(FR)La présente invention concerne la thérapie génique, et plus particulièrement, la thérapie génique à base d'adénovirus ainsi que des lignées cellulaires et des compositions apparentées. En particulier, l'invention traite de nouvelles lignées cellulaires d'enroulement pour faciliter le développement de vecteurs à grande capacité. L'invention traite aussi de divers vecteurs d'adénovirus à grande capacité, et de compositions et d'ensembles apparentés comprenant les lignées cellulaires et les vecteurs de l'invention. Enfin, l'invention a aussi pour objet des procédés de préparation et d'utilisation des vecteurs, des lignées cellulaires et des ensembles décrits.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)