Processing

Please wait...

Settings

Settings

Goto Application

1. WO1998013380 - SNRNP SM PROTEINS

Publication Number WO/1998/013380
Publication Date 02.04.1998
International Application No. PCT/US1997/017362
International Filing Date 26.09.1997
Chapter 2 Demand Filed 27.04.1998
IPC
A61K 39/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
C07K 14/47 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
CPC
A61K 39/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
A61P 37/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
C07K 14/4713
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
4701not used
4713Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
Applicants
  • INCYTE PHARMACEUTICALS, INC. [US]/[US] (AllExceptUS)
  • HILLMAN, Jennifer, L. [US]/[US] (UsOnly)
  • BANDMAN, Olga [US]/[US] (UsOnly)
  • ZWEIGER, Gary, B. [US]/[US] (UsOnly)
Inventors
  • HILLMAN, Jennifer, L.
  • BANDMAN, Olga
  • ZWEIGER, Gary, B.
Agents
  • BILLINGS, Lucy, J.
Priority Data
08/722,34927.09.1996US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SNRNP SM PROTEINS
(FR) PROTEINES SM SNRNP
Abstract
(EN)
The present invention provides novel human small nuclear ribonucleoprotein (snRNP) Sm proteins (collectively called HSMP) and polynucleotides which identify and encode HSMP. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HSMP. The invention also provides pharmaceutical compositions containing HSMP or antagonists to HSMP, and in the use of these compositions for the treatment of diseases associated with the expression of HSMP. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HSMP for the treatment of diseases associated with the expression of HSMP. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, to hybridize to the genomic sequence or transcripts of polynucleotides encoding HSMP or anti-HSMP antibodies which specifically bind to HSMP.
(FR)
La présente invention concerne de nouvelles protéines humaines Sm (appelées collectivement HSMP) de ribonucléoprotéines nucléaires de petite taille (snRNP), et des polynucléotides qui identifient et codent ces HSMP. Cette invention prévoit également des vecteurs d'expression mis au point génétiquement, et des cellules hôtes comprenant des séquences d'acides nucléiques codant des HSMP. Cette invention prévoit également des compositions pharmaceutiques contenant des HSMP ou des antagonistes de HSMP. De plus, cette invention prévoit l'utilisation de molécules antisens de polynucléotides codant des HSMP dans le traitement de maladies associées à l'expression de HSMP. Cette invention prévoit également des méthodes diagnostiques qui utilisent le polynucléotide, ou des fragments du complément de celui-ci, en vue d'une hybridation à la séquence génomique ou à des produits de transcription de polynucléotides codant des HSMP ou des anticorps anti-HSMP se liant spécifiquement à des HSMP.
Latest bibliographic data on file with the International Bureau