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Machine translation
1. (WO1998013035) PERCUTANEOUS PREPARATIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/013035    International Application No.:    PCT/JP1997/003412
Publication Date: 02.04.1998 International Filing Date: 25.09.1997
Chapter 2 Demand Filed:    23.02.1998    
IPC:
A61K 9/70 (2006.01), A61K 31/137 (2006.01)
Applicants: NITTO DENKO CORPORATION [JP/JP]; 1-2, Shimohozumi 1-chome, Ibaraki-shi, Osaka 567 (JP) (For All Designated States Except US).
HOKURIKU SEIYAKU CO., LTD. [JP/JP]; 37-1-1, Inokuchi, Katsuyama-shi, Fukui 911 (JP) (For All Designated States Except US).
NAKANO, Yoshihisa [JP/JP]; (JP) (For US Only).
YAMAMOTO, Keiji [JP/JP]; (JP) (For US Only).
NAKAGAWA, Takeaki [JP/JP]; (JP) (For US Only).
HORI, Mitsuhiko [JP/JP]; (JP) (For US Only).
OTSUKA, Saburo [JP/JP]; (JP) (For US Only)
Inventors: NAKANO, Yoshihisa; (JP).
YAMAMOTO, Keiji; (JP).
NAKAGAWA, Takeaki; (JP).
HORI, Mitsuhiko; (JP).
OTSUKA, Saburo; (JP)
Agent: TAKASHIMA, Hajime; Yuki Building, 3-9, Hiranomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 541 (JP)
Priority Data:
8/254293 26.09.1996 JP
Title (EN) PERCUTANEOUS PREPARATIONS
(FR) PREPARATIONS PERCUTANEES
Abstract: front page image
(EN)Percutaneous preparations composed of a support and a plaster layer located on one face thereof and containing 2-tert-butylamino-1-(2-chloro-4-hydroxy-phenyl)ethan-1-o1 or its pharmacologically acceptable salt and a pressure-sensitive adhesive, wherein the adhesive is an acrylic polymer substantially free from carboxy or comprises a material containing at least one high-molecular-weight rubber component with an average molecular weight of from 300,000 to 2,500,000 and at least one additive selected from among C¿12-18? fatty acid esters, C¿8-10? fatty acid monoglycerides and C¿6-10? dibasic acid esters. These percutaneous preparations are excellent in percutaneous drug-absorption properties, can give long-lasting drug effects with little side effect and, therefore, are useful in the prevention and treatment of threatened abortion, premature birth, urination disorders such as urinary incontinence, etc.
(FR)Préparations percutanées constituées d'un support, d'une couche d'emplâtre disposée sur une de ses faces et contenant du 2-tert-butylamino-1-(2-chloro-4-hydroxy-phényl)éthan-1-ol ou son sel pharmaceutiquement acceptable, et d'un adhésif autocollant. Ce dernier est un polymère acrylique sensiblement dépourvu de carboxy, ou il contient un matériau comprenant au moins un composant caoutchouc de poids moléculaire élevé, ayant un poids moléculaire moyen compris entre 300000 et 2500000, et au moins un additif choisi entre les esters d'acides gras C¿12?-C¿18?, les monoglycérides d'acides gras C¿8?-C¿10? et les esters de diacides C¿6?-C¿10?. Ces préparations percutanées ont d'excellentes propriétés en ce qui concerne l'absorption percutanée des médicaments, donnent des effets médicamenteux durables avec peu d'effets secondaires, et sont donc utiles pour la prévention et le traitement des menaces d'avortement, des naissances prématurées, ainsi que des troubles de la miction tels que l'incontinence urinaire, etc.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, HU, ID, IL, IS, KE, KG, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)