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Machine translation
1. (WO1998003672) N-(R)-(2-HYDROXY-2-PYRIDINE-3-YL-ETHYL)-2-(4-NITRO-PHENYL)-ACETAMIDE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/003672    International Application No.:    PCT/US1997/012615
Publication Date: 29.01.1998 International Filing Date: 18.07.1997
Chapter 2 Demand Filed:    20.02.1998    
IPC:
C07D 213/40 (2006.01), C12P 17/12 (2006.01)
Applicants: MERCK & CO., INC. [US/US]; 126 East Lincoln Avenue, Rahway, NJ 07065 (US) (For All Designated States Except US).
CHARTRAIN, Michel, M. [US/US]; (US) (For US Only).
CHUNG, John, Y., L. [US/US]; (US) (For US Only).
ROBERGE, Christopher [US/US]; (US) (For US Only)
Inventors: CHARTRAIN, Michel, M.; (US).
CHUNG, John, Y., L.; (US).
ROBERGE, Christopher; (US)
Common
Representative:
MERCK & CO., INC.; 126 East Lincoln Avenue, Rahway, NJ 07065 (US)
Priority Data:
60/022,055 22.07.1996 US
9616805.9 09.08.1996 GB
Title (EN) N-(R)-(2-HYDROXY-2-PYRIDINE-3-YL-ETHYL)-2-(4-NITRO-PHENYL)-ACETAMIDE
(FR) N-(R)-(2-HYDROXY-2-PYRIDINE-3-YL-ETHYL)-2-(4-NITRO-PHENYL)-ACETAMIDE
Abstract: front page image
(EN)Asymmetric bioreduction of a ketone substrate with yeast produces the corresponding (R)-alcohol of structure (I), a key intermediate in the synthesis of $g(b)3-agonist of structure (a).
(FR)La bioréduction asymétrique d'un substrat cétonique par de la levure produit le (R)-alcool correspondant dont la structure est représentée par la formule générale (I), et qui est un intermédiaire clé dans la synthèse d'un $g(b)3-agoniste dont la structure est représentée par la formule (a).
Designated States: AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CU, CZ, EE, GE, HU, IL, IS, JP, KG, KR, KZ, LC, LK, LR, LT, LV, MD, MG, MK, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, SL, TJ, TM, TR, TT, UA, US, UZ, VN, YU.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)