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1. (WO1998003669) VECTORS FOR INHIBITING HIV AND TUMOR GROWTH
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/003669    International Application No.:    PCT/US1997/012637
Publication Date: 29.01.1998 International Filing Date: 17.07.1997
Chapter 2 Demand Filed:    20.02.1998    
IPC:
A61K 48/00 (2006.01), C07K 14/16 (2006.01), C12N 9/22 (2006.01), C12N 15/85 (2006.01), C12N 15/867 (2006.01)
Applicants: THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES [US/US]; Bethesda, MD 20892 (US) (For All Designated States Except US).
RAYBAK, Susanna, M. [US/US]; (US) (For US Only).
CARA, Andrea [IT/US]; (US) (For US Only).
GUSELLA, Gabriele, Luca [IT/US]; (US) (For US Only).
NEWTON, Dianne, L. [US/US]; (US) (For US Only)
Inventors: RAYBAK, Susanna, M.; (US).
CARA, Andrea; (US).
GUSELLA, Gabriele, Luca; (US).
NEWTON, Dianne, L.; (US)
Agent: QUINE, Jonathan, A.; Townsend and Townsend and Crew LLP, 8th floor, Two Embarcadero Center, San Francisco, CA 94111 (US)
Priority Data:
60/022,052 22.07.1996 US
Title (EN) VECTORS FOR INHIBITING HIV AND TUMOR GROWTH
(FR) VECTEURS D'ADMINISTRATION D'INHIBITEURS DE CELLULES VIRALES ET ONCOGENES
Abstract: front page image
(EN)Cell transformation vectors for inhibiting HIV and tumor growth are provided. Optionally, the vectors encode RNAses such as EDN. Cells transduced by the vectors and methods of transforming cells ($i(in vitro) and $i(in vivo)) using the vectors are also provided.
(FR)La présente invention se rapporte à des vecteurs de transduction cellulaire conçus pour inhiber la croissance du virus de l'immunodéficience humaine et de tumeurs. Lesdits vecteurs peuvent éventuellement coder des ribonucléases du type neurotoxine dérivée d'éosinophiles (EDN $i(eosinophil-derived neurotoxin)). L'invention se rapporte également aux cellules transduites par ces vecteurs ainsi qu'à des procédés de transduction de cellules ($i(in vitro) et $i(in vivo)) faisant usage de ces vecteurs.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)