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1. (WO1998003509) DC-89 DERIVATIVES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/003509    International Application No.:    PCT/JP1997/002516
Publication Date: 29.01.1998 International Filing Date: 22.07.1997
Chapter 2 Demand Filed:    30.01.1998    
IPC:
C07D 487/04 (2006.01)
Applicants: KYOWA HAKKO KOGYO CO., LTD. [JP/JP]; 6-1, Ohtemachi 1-chome, Chiyoda-ku, Tokyo 100 (JP) (For All Designated States Except US).
AMISHIRO, Nobuyoshi [JP/JP]; (JP) (For US Only).
SAITO, Hiromitsu [JP/JP]; (JP) (For US Only).
OKAMOTO, Akihiko [JP/JP]; (JP) (For US Only).
GOMI, Katsushige [JP/JP]; (JP) (For US Only).
OKABE, Masami [JP/JP]; (JP) (For US Only)
Inventors: AMISHIRO, Nobuyoshi; (JP).
SAITO, Hiromitsu; (JP).
OKAMOTO, Akihiko; (JP).
GOMI, Katsushige; (JP).
OKABE, Masami; (JP)
Priority Data:
8/192634 23.07.1996 JP
Title (EN) DC-89 DERIVATIVES
(FR) DERIVES DE DC-89
Abstract: front page image
(EN)DC-89 derivatives represented by general formula (I) or pharmacologically acceptable salts thereof, (I) wherein (II) represents (III) or (IV) (wherein X represents C1 or Br; and R represents hydrogen or COR1), and W represents (V) or (VI). Because of having excellent antitumor effects, these compounds are useful as antitumor agents.
(FR)Dérivés de DC-89 de formule générale (I) ou sels pharmaceutiquement acceptables desdits dérivés. Dans ladite formule, la formule (II) représente la formule (III) ou (IV) dans lesquelles X représente Cl ou Br et R représente hydrogène ou COR1 et W représente la formule (V) ou (VI). Du fait de leurs excellents effets antitumoraux, ces composés sont utiles en tant qu'agents antitumoraux.
Designated States: AU, BG, BR, CA, CN, CZ, HU, JP, KR, MX, NO, NZ, PL, RO, SG, SI, SK, UA, US, VN.
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)