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Machine translation
1. (WO1998001422) NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/001422    International Application No.:    PCT/SE1997/001150
Publication Date: 15.01.1998 International Filing Date: 26.06.1997
Chapter 2 Demand Filed:    15.01.1998    
IPC:
C07C 309/73 (2006.01), C07C 311/21 (2006.01), C07C 311/29 (2006.01), C07C 323/60 (2006.01), C07D 233/84 (2006.01), C07D 261/16 (2006.01), C07D 333/34 (2006.01), C07F 9/53 (2006.01)
Applicants: ASTRA AKTIEBOLAG [SE/SE]; S-151 85 Södertälje (SE) (For All Designated States Except US).
ANTONSSON, Thomas [SE/SE]; (SE) (For US Only)
Inventors: ANTONSSON, Thomas; (SE)
Agent: PÅRUP, Mats; Astra Aktiebolag, Patent Dept., S-151 85 Södertälje (SE)
Priority Data:
9602646-3 04.07.1996 SE
Title (EN) NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS
(FR) NOUVEAUX DERIVES AMIDINO ET LEUR UTILISATION COMME INHIBITEURS DE LA THROMBINE
Abstract: front page image
(EN)There are provided compounds of formula (I), wherein R?1¿, R?2¿, R?3¿, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
(FR)L'invention concerne des composés de formule (I), dans laquelle R?1¿, R?2¿, R?3¿, Y, n et B ont la signification mentionnée dans la description. Ces composés sont utiles comme inhibiteurs compétitifs des protéases de type trypsine, telles que la thrombine, notamment pour le traitement des états où une inhibition de la thrombine est nécessaire (thrombose par exemple), ou comme anticoagulants.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)