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Machine translation
1. (WO1998001120) METHOD OF INHIBITING NADPH OXIDASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/001120    International Application No.:    PCT/US1997/011439
Publication Date: 15.01.1998 International Filing Date: 07.07.1997
Chapter 2 Demand Filed:    09.02.1998    
IPC:
A61K 31/136 (2006.01), A61K 31/15 (2006.01), A61K 31/433 (2006.01), A61K 31/444 (2006.01)
Applicants: IDUN PHARMACEUTICALS, INCORPORATED [US/US]; Suite 300, 11085 North Torrey Pines Road, La Jolla, CA 92037 (US)
Inventors: TERNANSKY, Robert, J.; (US).
VALENTINO, Karen, L.; (US).
KARANEWSKY, Donald, S.; (US)
Agent: HERMANNS, Karl, R.; Seed and Berry LLP, 6300 Columbia Center, 701 Fifth Avenue, Seattle, WA 98104 (US)
Priority Data:
08/676,822 08.07.1996 US
Title (EN) METHOD OF INHIBITING NADPH OXIDASE
(FR) METHODE D'INHIBITION DE L'OXYDASE DE NADPH
Abstract: front page image
(EN)The instant method employs pharmaceutical compositions comprising aromatic azines; and imines, of Formula (1) to selectively inhibit inflammation by preventing the oxidating burst from phagocytic leukocytes caused by NADPH Oxidase.
(FR)Selon les méthodes proposées par l'invention, on utilise des compositions pharmaceutiques comprenant des azines aromatiques et des imines répondant à la formule (1) pour inhiber sélectivement une inflammation, par prévention d'une salve d'oxydation provenant des leucocytes phagocitaires et provoquée par l'oxydage de NADPH.
Designated States: CA, JP.
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)