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Machine translation
1. (WO1998000425) PREPARATION OF (7S,TRANS)-2-(2-PYRIMIDINYL)-7-(HYDROXYMETHYL)OCTAHYDRO-2H-PYRIDO[1,2-A]PYRAZINE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/000425    International Application No.:    PCT/IB1997/000704
Publication Date: 08.01.1998 International Filing Date: 16.06.1997
Chapter 2 Demand Filed:    29.09.1997    
IPC:
C07D 471/04 (2006.01)
Applicants: PFIZER INC. [US/US]; 235 East 42nd Street, New York, NY 10017 (US) (For All Designated States Except US).
RUGGERI, Sally, Gut [US/US]; (US) (For US Only).
HAMMEN, Philip, Dietrich [US/US]; (US) (For US Only)
Inventors: RUGGERI, Sally, Gut; (US).
HAMMEN, Philip, Dietrich; (US)
Agent: SPIEGEL, Allen, J.; Pfizer Inc., Patent Dept., 235 East 42nd Street, New York, NY 10017 (US)
Priority Data:
60/020,511 01.07.1996 US
Title (EN) PREPARATION OF (7S,TRANS)-2-(2-PYRIMIDINYL)-7-(HYDROXYMETHYL)OCTAHYDRO-2H-PYRIDO[1,2-A]PYRAZINE
(FR) PREPARATION DE (7S,TRANS)-2-(2-PYRIMIDINYL)-7-(HYDROXYMETHYL)OCTAHYDRO-2H-PYRIDO[1,2-A]PYRAZINE
Abstract: front page image
(EN)A process for separating the enantiomers of a racemic mixture of trans-2-(2-pyrimidinyl)-7-(hydroxymethyl)octahydro-2H-pyrido[1,2-a]pyrazine comprising reacting the racemic mixture with D-(-) or L-(+) tartaric acid and separating the resulting diastereomeric tartrate salts.
(FR)Procédé de séparation des énantiomères d'un mélange racémique de trans-2-(2-pyrimidinyl)-7-(hydroxyméthyl)octahydro-2H-pyridol[1,2-a]pyrazine, qui consiste à effectuer la réaction du mélange racémique avec de l'acide tartarique D-(-) ou L-(+) et à séparer les sels diastéréomères de tartrate obtenus.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)