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Machine translation
1. (WO1998000141) METHODS AND COMPOSITIONS FOR TREATING URINARY INCONTINENCE USING ENANTIOMERICALLY ENRICHED (S)-TRIHEXYPHENIDYL
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/000141    International Application No.:    PCT/US1997/011643
Publication Date: 08.01.1998 International Filing Date: 27.06.1997
Chapter 2 Demand Filed:    30.01.1998    
IPC:
A61K 31/4453 (2006.01), C07D 295/084 (2006.01)
Applicants: SEPRACOR, INC. [US/US]; 111 Locke Drive, Marlborough, MA 01752 (US) (For All Designated States Except US).
FABIANO, Vincent, L. [US/US]; (US) (For US Only).
McCULLOUGH, John, R. [US/US]; (US) (For US Only)
Inventors: FABIANO, Vincent, L.; (US).
McCULLOUGH, John, R.; (US)
Agent: CLEMENT, Candice, J.; Heslin & Rothenberg, P.C., 5 Columbia Circle, Albany, NY 12203 (US)
Priority Data:
60/020,733 01.07.1996 US
Title (EN) METHODS AND COMPOSITIONS FOR TREATING URINARY INCONTINENCE USING ENANTIOMERICALLY ENRICHED (S)-TRIHEXYPHENIDYL
(FR) PROCEDES ET COMPOSITIONS DE TRAITEMENT DE L'INCONTINENCE URINAIRE PAR (S)-TRIHEXYPHENIDYLE ENRICHI EN ENANTIOMERE
Abstract: front page image
(EN)A method for treating urinary incontinence, such as incontinence resulting from bladder detrusor muscle instability, using enantiomerically enriched (S)-trihexyphenidyl. The method comprises administering a therapeutically effective amount of enantiomerically enriched (S)-trihexyphenidyl, or a pharmaceutically acceptable salt thereof, substantially free of the (R)-trihexyphenidyl enantiomer. Pharmaceutical compositions for the treatment of urinary incontinence comprising enantiomerically enriched (S)-trihexyphenidyl, or a pharmaceutically acceptable salt thereof, and an acceptable carrier are also disclosed.
(FR)L'invention porte sur un procédé de traitement de l'incontinence urinaire, telle que l'incontinence due à une instabilité du muscle vésical, par (S)-trihexyphénidyle enrichi en énantiomère. Le procédé consiste à administrer une dose efficace sur le plan thérapeutique de (S)-trihexyphénidyle enrichi en énantiomère, ou de sel pharmacologiquement acceptable de celui-ci, ledit sel étant sensiblement sans énantiomère de (R)-trihexyphénidyle. L'invention porte également sur des compositions pharmaceutiques destinées au traitement de l'incontinence urinaire et renfermant du (S)-trihexyphénidyle enrichi en énantiomère, ou un sel de celui-ci pharmacologiquement acceptable, ainsi que sur un excipient acceptable.
Designated States: US.
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)