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1. WO1997046235 - ANTI-VIRAL COMPOUNDS

Publication Number WO/1997/046235
Publication Date 11.12.1997
International Application No. PCT/US1997/008846
International Filing Date 05.06.1997
Chapter 2 Demand Filed 18.12.1997
IPC
C07D 235/30 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
24with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
30Nitrogen atoms not forming part of a nitro radical
CPC
A61P 31/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
C07D 235/30
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
24with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
30Nitrogen atoms not forming part of a nitro radical
Applicants
  • ELI LILLY AND COMPANY [US]/[US]
Inventors
  • JUNGHEIM, Louis, N.
  • MILLER, Shawn, C.
  • SPITZER, Wayne, A.
  • TEBBE, Mark, J.
  • VICTOR, Frantz
Agents
  • McCLAIN, Janet, T.
Priority Data
60/019,22406.06.1996US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ANTI-VIRAL COMPOUNDS
(FR) COMPOSES ANTIVIRAUX
Abstract
(EN)
The present application provides a series of benzimidazole compounds which inhibit the growth of picornaviruses, such as rhinoviruses, enteroviruses, polioviruses, coxsackieviruses of the A and B groups, echo virus and Mengo virus and flaviviruses such as hepatitis C and bovine diarrheal virus.
(FR)
L'invention porte sur une série de composés de benzimidazole inhibant la croissance des picornavirus tels que les rhinovirus, entérovirus, poliovirus, le virus Coxsackié des groupes A et B, l'échovirus, le virus de Mengo, et les flavivirus tels que l'hépatite C et le virus de la diarrhée bovine.
Latest bibliographic data on file with the International Bureau