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1. WO1997046208 - GENISTEIN AS A PREVENTIVE AGAINST ULTRAVIOLET INDUCED SKIN PHOTODAMAGE AND CANCER

Publication Number WO/1997/046208
Publication Date 11.12.1997
International Application No. PCT/US1997/011963
International Filing Date 09.06.1997
Chapter 2 Demand Filed 05.01.1998
IPC
A61K 8/49 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
49containing heterocyclic compounds
A61K 31/352 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 41/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
41Medicinal preparations obtained by treating materials with wave energy or particle radiation
A61Q 17/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
17Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
CPC
A61K 31/352
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 41/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
41Medicinal preparations obtained by treating materials with wave energy or particle radiation ; ; Therapies using these preparations
A61K 8/498
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
49containing heterocyclic compounds
4973with oxygen as the only hetero atom
498having 6-membered rings or their condensed derivatives, e.g. coumarin
A61P 17/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
A61Q 17/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
17Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
Applicants
  • MT. SINAI SCHOOL OF MEDICINE OF THE CITY OF NEW YORK [US]/[US]
Inventors
  • WEI, Huachen
Agents
  • CLARK, Richard, S.
Priority Data
08/657,91507.06.1996US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) GENISTEIN AS A PREVENTIVE AGAINST ULTRAVIOLET INDUCED SKIN PHOTODAMAGE AND CANCER
(FR) GENISTEINE UTILISEE COMMME AGENT PREVENTIF CONTRE LES PROBLEMES DE LA PEAU ET LES CANCERS DE LA PEAU INDUITS PAR LES RAYONS ULTRAVIOLETS
Abstract
(EN)
A method of inhibiting the harmful effect of UVR exposure to the human skin comprising topically applying a therapeutically effective amount of genistein to the skin at a time sufficiently close to the time of UVR exposure to inhibit UVR-induced damage to the skin. The genistein appears to act as a chemo preventative agent since it has no appreciable sun blocking effect. The genistein may be mixed with a variety of carriers and skin treatment compositions.
(FR)
Procédé d'inhibition des effets préjudiciables de l'exposition aux rayons UV de la peau d'êtres humains, consistant à appliquer localement une quantité thérapeutiquement efficace de génistéine sur la peau à un moment suffisant proche du moment d'exposition aux UV afin d'empêcher les rayons UV d'endommager la peau. La génistéine agit comme agent chimiopréventif étant donné qu'il n'a aucun effet appréciable de blocage des rayons solaires. La génistéine peut être mélangée à une variété d'excipients et de compositions de traitement de la peau.
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