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1. WO1997040388 - PEPTIDES HAVING SPECIFIC AFFINITY TO PACAP TYPE 1 RECEPTORS

Publication Number WO/1997/040388
Publication Date 30.10.1997
International Application No. PCT/JP1997/001394
International Filing Date 23.04.1997
Chapter 2 Demand Filed 27.10.1997
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/47 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
C07K 14/575 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
575Hormones
G01N 33/68 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/47
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
C07K 14/57563
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
575Hormones
57563Vasoactive intestinal peptide [VIP]; Related peptides
G01N 33/68
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
G01N 33/6842
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
6803General methods of protein analysis not limited to specific proteins or families of proteins
6842Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
Applicants
  • SHISEIDO COMPANY, LTD. [JP]/[JP]
  • THE GENERAL HOSPITAL CORPORATION [US]/[US]
Inventors
  • MORO, Osamu
  • WAKITA, Kawori
  • HYOCHI, Manami
  • LERNER, Ethan, A.
  • TAJIMA, Masahiro
Agents
  • ODAJIMA, Heikichi
Priority Data
08/637,43725.04.1996US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PEPTIDES HAVING SPECIFIC AFFINITY TO PACAP TYPE 1 RECEPTORS
(FR) PEPTIDES PRESENTANT UNE AFFINITE SPECIFIQUE POUR LES RECEPTEURS PACAP DE TYPE 1
Abstract
(EN)
This specification relates to use of peptides having a specific affinity to subtype 1 of PACAP (pituitary adenylate cyclase activating polypeptide) receptors, particularly MAX (67 amino acids), NSP (61 amino acids) and M 65 (46 amino acids). MAX and NSP act as agonists to PACAP type 1 receptors, and M 65 acts as an antagonist to PACAP type 1 receptors.
(FR)
La présente invention concerne l'utilisation de peptides présentant une affinité spécifique pour le sous-type 1 des récepteurs PACAP $i((Pituitary Adenylate Cyclase Activating Polypeptide)), en particulier MAX (67 acides aminés), NSP (61 acides aminés) et M 65 (67 acides aminés). MAX et NSP se comportent comme des agonistes des récepteurs PACAP de type 1, M 65 se comportant comme un antagoniste des récepteurs PACAP de type 1.
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