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Machine translation
1. (WO1997039629) VIRAL VECTORS INCLUDING POLYNUCLEOTIDES ENCODING NEUROTROPHIC FACTORS AND USES THEREFOR
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/039629    International Application No.:    PCT/US1997/006560
Publication Date: 30.10.1997 International Filing Date: 24.04.1997
Chapter 2 Demand Filed:    30.10.1997    
IPC:
A61K 38/18 (2006.01), A61K 48/00 (2006.01), C12N 15/861 (2006.01), C12N 15/867 (2006.01)
Applicants: GENETIC THERAPY, INC. [US/US]; 938 Clopper Road, Gaithersburg, MD 20878 (US) (For All Designated States Except US).
UNIVERSITY OF ROCHESTER [US/US]; 518 Hylan Building, Rochester, NY 14627-0140 (US) (For All Designated States Except US).
BOHN, Martha, C. [US/US]; (US) (For US Only).
CHOI-LUNDBERG, Derek [US/US]; (US) (For US Only).
LIN, Qing [CN/US]; (US) (For US Only).
FIGLEWICZ, Denise, A. [US/US]; (US) (For US Only).
CHANG, Yung-Nien [US/US]; (US) (For US Only).
CHIANG, Yawen, L. [US/US]; (US) (For US Only)
Inventors: BOHN, Martha, C.; (US).
CHOI-LUNDBERG, Derek; (US).
LIN, Qing; (US).
FIGLEWICZ, Denise, A.; (US).
CHANG, Yung-Nien; (US).
CHIANG, Yawen, L.; (US)
Agent: LILLIE, Raymond, J.; Carella, Byrne, Bain, Gilfillan, Cecchi, Stewart & Olstein, 6 Becker Farm Road, Roseland, NJ 07068 (US)
Priority Data:
08/636,548 25.04.1996 US
08/796,278 07.02.1997 US
Title (EN) VIRAL VECTORS INCLUDING POLYNUCLEOTIDES ENCODING NEUROTROPHIC FACTORS AND USES THEREFOR
(FR) VECTEURS VIRAUX INCLUANT DES POLYNUCLEOTIDES CODANT DES FACTEURS NEUROTROPHIQUES AINSI QUE LEUR UTILISATION
Abstract: front page image
(EN)Viral vectors such as, for example, retroviral vectors, adenoviral vectors, SV40 vectors, and Herpes Virus vectors, which include a polynucleotide encoding a neurotrophic factor, such as, glial cell line derived neurotrophic factor (GDNF). Such vectors may be employed in gene therapy procedures for the treatment of amyotrophic lateral sclerosis or Parkinson's Disease, wherein such vectors are employed in the $i(ex vivo) or $i(in vivo) transduction of cells.
(FR)Vecteurs viraux tels que les vecteurs rétroviraux, les vecteurs adénoviraux, les vecteurs de SV40 et les vecteurs du virus herpétique, qui incluent un polynucléotide codant un facteur neurotrophique tel que le GDNF (facteur neurotrophique dérivé des cellules gliales). Ces vecteurs peuvent être utilisés dans la thérapie génique pour le traitement de la sclérose latérale amyotrophique ou de la maladie de Parkinson; ils sont alors utilisés dans la transduction des cellules $i(ex vivo) ou $i(in vivo).
Designated States: AU, CA, JP, NZ, US.
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)