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Machine translation
1. (WO1997039136) METHODS TO ENHANCE THE ACTIVITY OF PEROXIDASE ENZYMES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/039136    International Application No.:    PCT/US1997/006559
Publication Date: 23.10.1997 International Filing Date: 18.04.1997
Chapter 2 Demand Filed:    14.11.1997    
IPC:
A62D 3/00 (2007.01), C12N 9/08 (2006.01)
Applicants: UTAH STATE UNIVERSITY FOUNDATION [US/US]; Suite 104, 1780 Research Parkway, Logan, UT 84332-9600 (US)
Inventors: SUTHERLAND, Greg, R., J.; (US).
AUST, Steven, D.; (US).
STAHL, James, D.; (US)
Agent: SEELEY, David, O.; Workman, Nydegger & Seeley, 1000 Eagle Gate Tower, 60 East South Temple, Salt Lake City, UT 84111 (US)
Priority Data:
60/015,618 18.04.1996 US
08/842,730 16.04.1997 US
Title (EN) METHODS TO ENHANCE THE ACTIVITY OF PEROXIDASE ENZYMES
(FR) PROCEDES AUGMENTANT L'ACTIVITE DES ENZYMES PEROXYDASES
Abstract: front page image
(EN)The present invention is directed to methods to enhance the rate and extent of biodegradation of organic compounds by peroxidase enzymes such as those produced by lignin-degrading fungi and particularly by white rot fungi. It has been discovered that metal ions can stabilize the enzymes to the effects of increasing temperature and increasing pH. In particular, this invention involves the use of divalent metal ions, preferably calcium and manganese ions, to enhance the rate and the extent of biotransformation and biodegradation reactions, such as the biodegradation of environmental pollutants, by white rot fungi or, more specifically, by peroxidase enzymes derived from white rot fungi.
(FR)La présente invention concerne des procédés visant à accroître la vitesse et l'étendue de la biodégradation de composés organiques par des enzymes peroxydase telles que celles obtenues par des champignons dégradant la lignine et notamment par des champignons de pourriture blanche. On a découvert que des ions métal peuvent stabiliser les enzymes contre les effets d'élévation de température et d'augmentation du pH. Cette invention concerne notamment l'utilisation d'ions métal divalents, de préférence des ions calcium et manganèse, qui permettent d'accroître la vitesse et l'étendue des réactions de biotransformation et de biodégradation telles que la biodégradation des polluants de l'environnement, par des champignons de pourriture blanche, ou plus spécifiquement, par des enzymes peroxydases dérivées des champignons de pourriture blanche.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, UZ, VN, YU.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)