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1. WO1997038705 - N-FORMYL HYDROXYLAMINE CONTAINING COMPOUNDS USEFUL AS ACE INHIBITORS AND/OR NEP INHIBITORS

Publication Number WO/1997/038705
Publication Date 23.10.1997
International Application No. PCT/US1997/005744
International Filing Date 07.04.1997
Chapter 2 Demand Filed 27.10.1997
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 5/02 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
5Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
02containing at least one abnormal peptide link
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
A61P 9/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
A61P 9/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
12Antihypertensives
C07K 5/0202
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
5Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
02containing at least one abnormal peptide link
0202containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
Applicants
  • BRISTOL-MYERS SQUIBB COMPANY [US]/[US]
Inventors
  • ROBL, Jeffrey, A.
Agents
  • RODNEY, Burton
Priority Data
60/016,29512.04.1996US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) N-FORMYL HYDROXYLAMINE CONTAINING COMPOUNDS USEFUL AS ACE INHIBITORS AND/OR NEP INHIBITORS
(FR) COMPOSES A BASE DE N-FORMYL HYDROXYLAMINE CONVENANT COMME INHIBITEURS DE L'ENZYME ACE ET/OU DE L'ENDOPEPTIDASE NEP
Abstract
(EN)
N-formyl hydroxylamines are provided which have structure (I) wherein R and R1 are as defined herein and A is a dipeptide derived from an amino acid or is a conformationally restricted dipeptide mimic.
(FR)
La présente invention concerne des n-formyl hydroxylamines représentés par la structure (I). R et R1 sont conformes à la description qui en est donnée dans la demande, et A est un dipeptide dérivé d'un acide aminé ou est un dipeptide mimique à conformation restreinte.
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