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Machine translation
1. (WO1997038665) INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/038665    International Application No.:    PCT/US1997/006487
Publication Date: 23.10.1997 International Filing Date: 27.03.1997
Chapter 2 Demand Filed:    30.10.1997    
IPC:
C07D 211/62 (2006.01), C07D 401/06 (2006.01), C07D 401/12 (2006.01), C07D 401/14 (2006.01), C07D 413/14 (2006.01)
Applicants: MERCK & CO., INC. [US/US]; 126 East Lincoln Avenue, Rahway, NJ 07065 (US) (For All Designated States Except US).
ANTHONY, Neville, J. [GB/US]; (US) (For US Only).
DINSMORE, Christopher [US/US]; (US) (For US Only).
GOMEZ, Robert, P. [US/US]; (US) (For US Only).
HUTCHINSON, John, H. [CA/US]; (US) (For US Only).
WAI, John, S. [GB/US]; (US) (For US Only).
WILLIAMS, Theresa, M. [US/US]; (US) (For US Only).
BELL, Ian, M. [GB/US]; (US) (For US Only).
EMBREY, Mark, W. [US/US]; (US) (For US Only).
FISHER, Thorsten, E. [US/US]; (US) (For US Only)
Inventors: ANTHONY, Neville, J.; (US).
DINSMORE, Christopher; (US).
GOMEZ, Robert, P.; (US).
HUTCHINSON, John, H.; (US).
WAI, John, S.; (US).
WILLIAMS, Theresa, M.; (US).
BELL, Ian, M.; (US).
EMBREY, Mark, W.; (US).
FISHER, Thorsten, E.; (US)
Common
Representative:
MERCK & CO., INC.; 126 East Lincoln Avenue, Rahway, NJ 07065 (US)
Priority Data:
60/014,791 03.04.1996 US
9609981.7 13.05.1996 GB
Title (EN) INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
(FR) INHIBITEURS DE LA FARNESYL-PROTEINE TRANSFERASE
Abstract: front page image
(EN)The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
(FR)Cette invention a trait à des composés inhibant la farnésyl-protéine transférase (FTase) et la farnélysation de la protéine oncogène Ras. Cette invention a trait, de surcroît, à des compositions à usage chimiothérapeutique contenant les composés selon cette invention ainsi qu'à des procédés visant à inhiber la farnésyl-protéine transférase et la farnélysation de la protéine oncogène Ras.
Designated States: AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CU, CZ, EE, GE, HU, IL, IS, JP, KG, KR, KZ, LC, LK, LR, LT, LV, MD, MG, MK, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, TJ, TM, TR, TT, UA, US, UZ, VN, YU.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)