WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO1997038664) A METHOD OF TREATING CANCER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/038664    International Application No.:    PCT/US1997/006248
Publication Date: 23.10.1997 International Filing Date: 15.04.1997
Chapter 2 Demand Filed:    23.10.1997    
IPC:
A61K 38/00 (2006.01), A61K 38/05 (2006.01), A61K 38/06 (2006.01), C07D 233/26 (2006.01), C07D 295/192 (2006.01), C07D 309/30 (2006.01), C07D 401/12 (2006.01), C07D 403/06 (2006.01), C07D 403/14 (2006.01)
Applicants: MERCK & CO., INC. [US/US]; 126 East Lincoln Avenue, Rahway, NJ 07065 (US) (For All Designated States Except US).
GIBBS, Jackson, B. [US/US]; (US) (For US Only).
KOHL, Nancy, E. [US/US]; (US) (For US Only).
OLIFF, Allen, I. [US/US]; (US) (For US Only)
Inventors: GIBBS, Jackson, B.; (US).
KOHL, Nancy, E.; (US).
OLIFF, Allen, I.; (US)
Common
Representative:
MERCK & CO., INC.; 126 East Lincoln Avenue, Rahway, NJ 07065 (US)
Priority Data:
60/015,589 18.04.1996 US
9611982.1 07.06.1996 GB
Title (EN) A METHOD OF TREATING CANCER
(FR) METHODE DE TRAITEMENT DE CANCER
Abstract: front page image
(EN)The present invention relates to a method of treating cancer which comprises administering to a mammalian patient an effective amount of a combination of geranylgeranyl-protein transferase-type I inhibitor and a farnesyl protein transferase inhibitor. The invention further relates to a method of treating cancer which comprises administering to a mammalian patient an effective amount of a combination of a selective geranylgeranyl-protein transferase-type I inhibitor and a selective farnesyl protein transferase inhibitor. The figure shows the autoradiograph of the immunoprecipates from assay set No. 1 of the $i(in vivo) prenylation inhibition by a combination by a selective of FPTase inhibitor and a selective geranylgeranyl-protein transferase-type I inhibitor.
(FR)Méthode de traitement anticancéreux consistant à administrer à un patient mammifère une dose efficace d'une combinaison composée d'un inhibiteur de géranylgéranyle-protéine transférase-tpye I et un inhibiteur de farnésyle protéine transférase. L'invention porte en outre sur une méthode de traitement du cancer consistant à administrer à un patient mammifère une dose efficace d'une combinaison d'un inhibiteur sélectif de géranylgéranyle-protéine transférase-type I et d'un inhibiteur sélectif de farnésyle protéine transférase.
Designated States: AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CU, CZ, EE, GE, HU, IL, IS, JP, KG, KR, KZ, LC, LK, LR, LT, LV, MD, MG, MK, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, TJ, TM, TR, TT, UA, US, UZ, VN, YU.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)