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Machine translation
1. (WO1997038579) EMULSIONS OF PERFLUORO COMPOUNDS AS SOLVENTS FOR NITRIC OXIDE (NO)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/038579    International Application No.:    PCT/US1997/006527
Publication Date: 23.10.1997 International Filing Date: 16.04.1997
Chapter 2 Demand Filed:    17.11.1997    
IPC:
A61K 9/00 (2006.01), A61K 33/00 (2006.01)
Applicants: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM [US/US]; 201 West 7th Street, Austin, TX 78701 (US) (For All Designated States Except US).
THE TEXAS A & M UNIVERSITY SYSTEM [US/US]; 310 Wisenbaker, College Station, TX 77843-3369 (US) (For All Designated States Except US).
GARFIELD, Robert, E. [US/US]; (US) (For US Only).
BALABAN, Alexandru, T. [RO/RO]; (RO) (For US Only).
SEITZ, William, A. [US/US]; (US) (For US Only)
Inventors: GARFIELD, Robert, E.; (US).
BALABAN, Alexandru, T.; (RO).
SEITZ, William, A.; (US)
Agent: HODGINS, Daniel, S.; Arnold, White & Durkee, P.O. Box 4433, Houston, TX 77210 (US)
Priority Data:
08/633,337 17.04.1996 US
Title (EN) EMULSIONS OF PERFLUORO COMPOUNDS AS SOLVENTS FOR NITRIC OXIDE (NO)
(FR) EMULSIONS DE COMPOSES PERFLUORO EN TANT QUE SOLVANTS POUR L'OXYDE NITRIQUE (NO)
Abstract: front page image
(EN)The present invention involves perfluoro compound emulsions including nitric oxide, their preparation and their use. These emulsions provide a new source of nitric oxide. Such nitric oxide-containing emulsions maybe used for the administration of nitric oxide to individuals in need thereof. Individuals in need of nitric oxide administration can include those suffering from hypertension, preeclampsia and a number of other situations where an increased blood flow, for example, is desirable. In addition, given the long use of perfluoro compound emulsions as blood substitutes, the present invention provides a relatively safe mode for administering and distributing nitric oxide, (see Figure 1) - without potential negative side effects such as toxicities due to drug metabolites.
(FR)L'invention décrit des émulsions de composés perfluoro y compris l'oxyde nitrique, leur préparation et leur utilisation. Ces émulsions constituent une nouvelle source d'oxyde nitrique. De telles émulsions contenant de l'oxyde nitrique peuvent être utilisées pour administrer de l'oxyde nitrique à des individus qui en ont besoin. Des individus à qui il est nécessaire d'administrer de l'oxyde nitrique sont ceux qui souffrent de l'hypertension, de la prééclampsie et d'autres états pathologiques où il est souhaitable d'accroître le flux sanguin. De plus, étant donné la longue utilisation d'émulsions de composés perfluoro en tant que substituts sanguins, la présente invention offre un mode relativement sûr d'administration et de distribution d'oxydes nitriques (figure 1), sans les effets secondaires négatifs tels que les toxicités dues aux métabolites des médicaments.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)