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Machine translation
1. (WO1997038114) PUROMYCIN-SENSITIVE AMINOPEPTIDASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/038114    International Application No.:    PCT/EP1996/001518
Publication Date: 16.10.1997 International Filing Date: 09.04.1996
IPC:
C07K 16/40 (2006.01), C12N 9/48 (2006.01)
Applicants: NOVARTIS AG [CH/CH]; Schwarzwaldallee 215, CH-4058 Basel (CH) (For All Designated States Except US).
FONTANA, Adriano [CH/CH]; (CH) (For US Only).
CONSTAM, Daniel, Beat [CH/US]; (US) (For US Only).
TOBLER, Andreas, Rudolf [CH/US]; (US) (For US Only).
ALTMANN, Karl-Heinz [DE/CH]; (CH) (For US Only).
SCHLAPBACH, Ralph [CH/CH]; (CH) (For US Only)
Inventors: FONTANA, Adriano; (CH).
CONSTAM, Daniel, Beat; (US).
TOBLER, Andreas, Rudolf; (US).
ALTMANN, Karl-Heinz; (CH).
SCHLAPBACH, Ralph; (CH)
Common
Representative:
NOVARTIS AG; Patent and Trademark Dept., Klybeckstrasse 141, CH-4002 Basle (CH)
Priority Data:
Title (EN) PUROMYCIN-SENSITIVE AMINOPEPTIDASES
(FR) AMINOPEPTIDASES SENSIBLES A LA PUROMYCINE
Abstract: front page image
(EN)The present invention relates to puromycin-sensitive aminopeptidases, antibodies generated against said aminopeptidases, and to means and methods for the production thereof. The invention is also directed to nucleic acids coding for said aminopeptidases, and fragments thereof, to methods of obtaining such nucleic acid molecules or fragments of the invention, and to systems suitable for the expression of such nucleic acids. One particular aspect of this invention relates to deoxyribo- and ribo-oligonucleotides and derivatives thereof, as well as pharmaceutical preparations, therapies, diagnostics and commercial research reagents in relation to disease states which respond to modulation of the synthesis of the enzyme puromycin-sensitive aminopeptidase (PSA).
(FR)Aminopeptidases sensibles à la puromycine, anticorps produits contre lesdites aminopeptidases et procédés et moyens de production desdites substances. La présente invention concerne également des acides nucléiques codant lesdites aminopeptidases et des fragments de ces dernières, des procédés permettant d'obtenir les molécules et fragments d'acides nucléiques de la présente invention et des systèmes appropriés à l'expression desdits acides nucléiques. Selon un de ses aspects particuliers, la présente invention concerne des désoxyribonucléotides et ribonucléotides et des dérivés de ces substances, ainsi que des préparations pharmaceutiques, des thérapies, des diagnostiques et des réactifs de recherche commerciaux, en relation avec des états pathologiques qui répondent à la modulation de la synthèse de l'enzyme aminopeptidase (PSA) sensible à la puromycine.
Designated States: AL, AU, BB, BG, BR, CA, CN, CZ, EE, GE, HU, IS, JP, KP, KR, LK, LR, LT, LV, MG, MK, MN, MX, NO, NZ, PL, RO, SG, SI, SK, TR, TT, UA, US, UZ, VN.
African Regional Intellectual Property Organization (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)