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Machine translation
1. (WO1997037966) QUATERNARY CYTOFECTINS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/037966    International Application No.:    PCT/US1997/005757
Publication Date: 16.10.1997 International Filing Date: 08.04.1997
Chapter 2 Demand Filed:    24.10.1997    
IPC:
A61K 48/00 (2006.01), C07C 217/08 (2006.01), C12N 15/88 (2006.01)
Applicants: VICAL INCORPORATED [US/US]; Suite 100, 9373 Towne Centre Drive, San Diego, CA 92121 (US)
Inventors: WHEELER, Carl. J.; (US)
Agent: ALTMAN, Daniel, E.; Knobbe, Martens, Olson & Bear, 16th floor, 620 Newport Center Drive, Newport Beach, CA 92660 (US)
Priority Data:
08/629,965 09.04.1996 US
Title (EN) QUATERNARY CYTOFECTINS
(FR) CYTOFECTINES QUATERNAIRES
Abstract: front page image
(EN)Cationic lipids, having a derivatized quaternary ammonium head group, that provide improved cell targeting ability and enhanced transfective efficacy for the delivery of molecules into cells. The lipids comprise a linker having funtional groups that provide sites for further attachment of drugs, cell receptor ligands or other bioactive agents.
(FR)Cette invention concerne des lipides cationiques possédant un groupe tête d'ammonium quaternaire dérivé qui améliorent la capacité de ciblage de cellules et l'efficacité transgénique pour apporter des molécules dans des cellules. Les lipides comprennent une séquence de liaison comportant des groupes fonctionnels qui servent de sites pour la fixation d'autres substances thérapeutiques, d'autres ligands de récepteur cellulaire ou d'autres agents bioactifs.
Designated States: CA, JP.
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)