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Machine translation
1. (WO1997037223) IDENTIFICATION AND ISOLATION OF NOVEL POLYPEPTIDES HAVING WW DOMAINS AND METHODS OF USING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/037223    International Application No.:    PCT/US1997/005547
Publication Date: 09.10.1997 International Filing Date: 03.04.1997
Chapter 2 Demand Filed:    28.10.1997    
IPC:
C12N 9/00 (2006.01), G01N 33/68 (2006.01)
Applicants: CYTOGEN CORPORATION [US/US]; 600 College Road East, Princeton, NJ 08540 (US).
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL [US/US]; Office of Technology and Development, CB#4100, 302 Bynum Hall, Chapel Hill, NC 27599-4105 (US)
Inventors: PIROZZI, Gregorio; (US).
KAY, Brian, K.; (US).
FOWLKES, Dana, M.; (US)
Agent: ANTLER, Adriane, M.; Pennie & Edmonds L.L.P., 1155 Avenue of the Americas, New York, NY 10036 (US)
Priority Data:
08/630,916 03.04.1996 US
Title (EN) IDENTIFICATION AND ISOLATION OF NOVEL POLYPEPTIDES HAVING WW DOMAINS AND METHODS OF USING SAME
(FR) IDENTIFICATION ET ISOLEMENT DE NOUVEAUX POLYPEPTIDES AYANT DES DOMAINES WW ET PROCEDES D'UTILISATION
Abstract: front page image
(EN)Novel polypeptides having WW domains of interest are described, along with DNA sequences that encode the same. A method of identifying these polypeptides by means of a sequence-independent (that is, independent of the primary sequence of the polypeptide sought), recognition unit-based functional screen is also disclosed. Various applications of the method and of the polypeptides identified are described, including their use in assay kits for drug discovery, modification, and refinement.
(FR)La présente invention décrit de nouveaux polypeptides ayant des domaines WW, ainsi que des séquences d'ADN codant pour lesdits polypeptides. Le procédé permet d'identifier les polypeptides au moyen d'un dispositif indépendant de la séquence (autrement dit, indépendant de la séquence primaire du polypeptide recherché), ainsi qu'un dispositif de crible fonctionnel basé sur une unité de reconnaissance. L'invention décrit également diverses applications du procédé et des polypeptides identifiés, y compris leur utilisation en kits d'analyse pour la découverte, la modification et le raffinage de médicaments.
Designated States: AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CU, CZ, EE, GE, GH, HU, IL, IS, JP, KG, KP, KR, KZ, LC, LK, LR, LT, LV, MD, MG, MK, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, TJ, TM, TR, TT, UA, UZ, VN, YU.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)