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Machine translation
1. (WO1997036897) INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1997/036897 International Application No.: PCT/US1997/005358
Publication Date: 09.10.1997 International Filing Date: 01.04.1997
Chapter 2 Demand Filed: 24.10.1997
IPC:
C07D 233/54 (2006.01) ,C07D 233/70 (2006.01) ,C07D 401/14 (2006.01) ,C07D 403/10 (2006.01) ,C07D 403/14 (2006.01) ,C07D 409/14 (2006.01) ,C07D 413/06 (2006.01) ,C07D 417/06 (2006.01) ,C07D 417/14 (2006.01)
Applicants: ANTHONY, Neville, J.[GB/US]; US (UsOnly)
MERCK & CO., INC.[US/US]; 126 East Lincoln Avenue Rahway, NJ 07065, US (AllExceptUS)
Inventors: ANTHONY, Neville, J.; US
Common
Representative:
MERCK & CO., INC.; 126 East Lincoln Avenue Rahway, NJ 07065, US
Priority Data:
60/014,59203.04.1996US
60/022,55824.07.1996US
9613462.227.06.1996GB
9617258.016.08.1996GB
Title (EN) INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
(FR) INHIBITEURS DE LA FARNESYL-PROTEINE TRANSFERASE
Abstract:
(EN) The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
(FR) L'invention concerne des composés qui inhibent la farnésyl-protéine transférase (FTase) et la farnésylation de la protéine oncogène Ras. Elle concerne également des compositions chimiothérapiques contenant ces composés et des procédés permettant d'inhiber la farnésyl-protéine transférase, ainsi que la farnésylation de la protéine oncogène Ras.
Designated States: AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CU, CZ, EE, GE, HU, IL, IS, JP, KG, KR, KZ, LC, LK, LR, LT, LV, MD, MG, MK, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, TJ, TM, TR, TT, UA, US, UZ, VN, YU
African Regional Intellectual Property Organization (ARIPO) (GH, KE, LS, MW, SD, SZ, UG)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)