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Machine translation
1. (WO1997036892) INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/036892    International Application No.:    PCT/US1997/005060
Publication Date: 09.10.1997 International Filing Date: 27.03.1997
Chapter 2 Demand Filed:    24.10.1997    
IPC:
A61K 31/4178 (2006.01), C07D 233/54 (2006.01), C07D 401/06 (2006.01)
Applicants: MERCK & CO., INC. [US/US]; 126 East Lincoln Avenue, Rahway, NJ 07065 (US) (For All Designated States Except US).
DINSMORE, Christopher, J. [US/US]; (US) (For US Only).
WILLIAMS, Theresa, M. [US/US]; (US) (For US Only)
Inventors: DINSMORE, Christopher, J.; (US).
WILLIAMS, Theresa, M.; (US)
Common
Representative:
MERCK & CO., INC.; 126 East Lincoln Avenue, Rahway, NJ 07065 (US)
Priority Data:
60/014,777 03.04.1996 US
9616736.6 09.08.1996 GB
Title (EN) INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
(FR) INHIBITEURS DE FARNESYLE-PROTEINE TRANSFERASE
Abstract: front page image
(EN)The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
(FR)La présente invention concerne des composés inhibant la farnésyle-protéine transférase (FTase) ainsi que la farnésylation de la protéine Raz oncogène. L'invention concerne également des compositions chimiothérapeutiques contenant les composés de ladite invention ainsi que des méthodes inhibant la farnésyle-protéine transférase et la farnésylation de la protéine Ras oncogène.
Designated States: AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CU, CZ, EE, GE, HU, IL, IS, JP, KG, KR, KZ, LC, LK, LR, LT, LV, MD, MG, MK, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, TJ, TM, TR, TT, UA, US, UZ, VN, YU.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)