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Machine translation
1. (WO1997036875) INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/036875    International Application No.:    PCT/US1997/005383
Publication Date: 09.10.1997 International Filing Date: 01.04.1997
Chapter 2 Demand Filed:    24.10.1997    
IPC:
C07D 213/57 (2006.01), C07D 233/54 (2006.01), C07D 233/70 (2006.01), C07D 401/14 (2006.01), C07D 403/10 (2006.01), C07D 403/14 (2006.01), C07D 409/10 (2006.01), C07D 409/14 (2006.01), C07D 413/06 (2006.01), C07D 417/06 (2006.01), C07D 417/14 (2006.01)
Applicants: MERCK & CO., INC. [US/US]; 126 East Lincoln Avenue, Rahway, NJ 07065 (US) (For All Designated States Except US).
ANTHONY, Neville, J. [GB/US]; (US) (For US Only).
STOKKER, Gerald, E. [US/US]; (US) (For US Only).
GOMEZ, Robert, P. [US/US]; (US) (For US Only).
SOLINSKY, Kelly, M. [US/US]; (US) (For US Only).
WAI, John, S. [GB/US]; (US) (For US Only).
WILLIAMS, Theresa, M. [US/US]; (US) (For US Only).
YOUNG, Steven, D. [US/US]; (US) (For US Only).
HUTCHINSON, John, H. [US/US]; (US) (For US Only).
HALCZENKO, Wasyl [US/US]; (US) (For US Only)
Inventors: ANTHONY, Neville, J.; (US).
STOKKER, Gerald, E.; (US).
GOMEZ, Robert, P.; (US).
SOLINSKY, Kelly, M.; (US).
WAI, John, S.; (US).
WILLIAMS, Theresa, M.; (US).
YOUNG, Steven, D.; (US).
HUTCHINSON, John, H.; (US).
HALCZENKO, Wasyl; (US)
Common
Representative:
MERCK & CO., INC.; 126 East Lincoln Avenue, Rahway, NJ 07065 (US)
Priority Data:
60/014,592 03.04.1996 US
9613462.2 27.06.1996 GB
60/022,582 24.07.1996 US
9617257.2 16.08.1996 GB
Title (EN) INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
(FR) INHIBITEURS DE LA FARNESYL-PROTEINE TRANSFERASE
Abstract: front page image
(EN)The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
(FR)L'invention concerne des composés qui inhibent la farnésyl-protéine transférase (FTase) et la farnésylation de la protéine oncogène Ras. Elle concerne également des compositions chimiothérapiques contenant ces composés et des procédés permettant d'inhiber la farnésyl-protéine transférase, ainsi que la farnésylation de la protéine oncogène Ras.
Designated States: AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CU, CZ, EE, GE, HU, IL, IS, JP, KG, KR, KZ, LC, LK, LR, LT, LV, MD, MG, MK, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, TJ, TM, TR, TT, UA, US, UZ, VN, YU.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)