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1. (WO1997035978) PARTIAL INTRON SEQUENCE OF VON HIPPEL-LINDAU (VHL) DISEASE GENE AND ITS USE IN DIAGNOSIS OF DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1997/035978 International Application No.: PCT/US1997/005059
Publication Date: 02.10.1997 International Filing Date: 27.03.1997
Chapter 2 Demand Filed: 01.10.1997
IPC:
C07K 14/47 (2006.01) ,C07K 16/18 (2006.01) ,C12Q 1/68 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES [US/US]; Office of Technology Transfer, National Institutes of Health, Suite 325, 6001 Executive Boulevard Rockville, MD 20852, US
Inventors:
LINEHAN, Marston, W.; US
LERMAN, Michael, I.; US
LATIF, Farida; US
ZBAR, Berton; US
Agent:
FEILER, William, S. ; Morgan & Finnegan, L.L.P. 345 Park Avenue New York, NY 10154, US
Priority Data:
08/623,42828.03.1996US
Title (EN) PARTIAL INTRON SEQUENCE OF VON HIPPEL-LINDAU (VHL) DISEASE GENE AND ITS USE IN DIAGNOSIS OF DISEASE
(FR) SEQUENCE D'INTRONS PARTIELLE DU GENE DE LA MALADIE DE VON HIPPEL-LINDAU (VHL) ET SON UTILISATION DANS LE DIAGNOSTIC DE MALADIES
Abstract:
(EN) The Von Hippel-Lindau (VHL) disease gene and its corresponding cDNA are disclosed. Methods for detecting carriers of the VHL disease gene using probes derived from the VHL disease gene sequence are described. Pharmaceutical compositions and methods of treating diseases related to the VHL gene are also disclosed.
(FR) L'invention se rapporte au gène de la maladie de Von Hippel-Lindau (VHL) et à son ADNc correspondant. Des procédés de détection des porteurs du gène de la maladie de VHL au moyen de sondes dérivées de la séquence génétique de cette maladie sont également décrits, ainsi que des compositions pharmaceutiques et des méthodes de traitement de maladies associées au gène de VHL.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, UZ, VN
African Regional Intellectual Property Organization (ARIPO) (GH, KE, LS, MW, SD, SZ, UG)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)