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Machine translation
1. (WO1997031633) METHODS OF TREATING OR PREVENTING SLEEP APNEA
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/031633    International Application No.:    PCT/US1997/003028
Publication Date: 04.09.1997 International Filing Date: 26.02.1997
Chapter 2 Demand Filed:    01.10.1997    
IPC:
A61K 31/454 (2006.01), A61K 31/4545 (2006.01), A61K 31/496 (2006.01), C07D 209/14 (2006.01)
Applicants: ELI LILLY AND COMPANY [US/US]; Lilly Corporate Center, Indianapolis, IN 46285 (US) (For All Designated States Except US).
GITTER, Bruce, D. [US/US]; (US) (For US Only).
IYENGAR, Smriti [IN/US]; (US) (For US Only)
Inventors: GITTER, Bruce, D.; (US).
IYENGAR, Smriti; (US)
Agent: GAYLO, Paul, J.; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285 (US)
Priority Data:
60/012,661 01.03.1996 US
Title (EN) METHODS OF TREATING OR PREVENTING SLEEP APNEA
(FR) METHODE POUR TRAITER OU PREVENIR LA DYSPNEE DU SOMMEIL
Abstract: front page image
(EN)This invention provides methods for the treatment or prevention of sleep apnea in a mammal which comprise administering to a mammal in need thereof an effective amount of a compound of formula (I) where R?1¿ and R?2¿ are independently selected from the group consisting of hydrogen, methyl, methoxy, chloro, and trifluoromethyl, with the proviso that no more than one of R?1¿ and R?2¿ can be hydrogen; and Y is (a), (b), (c), (d), (e), (f), N-R?a¿, or CH-NR?b¿R?c¿, where R?a¿, R?b¿, and R?c¿ are independently selected from the group consisting of hydrogen and C¿1?-C¿6? alkyl; or a pharmaceutically acceptable salt or solvate thereof.
(FR)L'invention concerne des méthodes permettant de traiter ou de prévenir la dyspnée du sommeil chez un mammifère, qui comprend l'administration à un mammifère en ayant besoin d'une quantité efficace d'un composé de formule (1), où R?1¿ et R?2¿ sont sélectionnés indépendamment dans le groupe constitué d'hydrogène, méthyle, méthoxy, chloro et trifluorométhyle, à condition que R?1¿ ou R?2¿ seulement puisse être hydrogène; et où Y est (a), (b), (c), (d), (e), (f), N-R?a¿ ou CH-NR?b¿R?c¿, où R?a¿, R?b¿ et R?c¿ sont sélectionnés indépendamment dans le groupe constitué d'hydrogène et d'alkyle C¿1?-C¿6?. L'invention concerne également un sel et un solvate pharmaceutiquement acceptables dudit composé.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, US, UZ, YU.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)