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1. WO1997030702 - METHOD OF INCREASING THE CONVERSION OF HOMOCYSTEINE TO METHIONINE AND USES THEREOF

Publication Number WO/1997/030702
Publication Date 28.08.1997
International Application No. PCT/US1997/002844
International Filing Date 24.02.1997
Chapter 2 Demand Filed 19.09.1997
IPC
A61K 31/205 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
205Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
CPC
A61K 31/205
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
205Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
Applicants
  • THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS [US]/[US]
Inventors
  • GARROW, A., Timothy
Agents
  • ADLER, Benjamin, A.
Priority Data
08/605,94023.02.1996US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD OF INCREASING THE CONVERSION OF HOMOCYSTEINE TO METHIONINE AND USES THEREOF
(FR) TRAITEMENT ACCROISSANT LA CONVERSION DE L'HOMOCYSTEINE EN METHIONINE ET SES APPLICATIONS
Abstract
(EN)
The present invention provides a method of decreasing total plasma homocyst(e)ine levels in an animal in need of such treatment, comprising the step of administering to said animal a pharmacologically effective dose of a thetin. Further provided is a method of treating hyperhomocyst(e)inemia in an animal in need of such treatment, comprising the step of administering to said animal a pharmacologically effective dose of a thetin. Also provided are novel pharmaceutical and nutritional compositions. Further provided is a method of reducing or eliminating the costly supplementation of methionine, choline, and betaine to protein-containing animal feeds.
(FR)
La présente invention concerne un traitement permettant de faire baisser les niveaux d'homocystéine dans le plasma total d'un animal justifiant d'un tel traitement, ce traitement consistant en l'administration d'une dose pharmacologiquement efficace de thétine à l'animal concerné. L'invention concerne également un traitement de l'hypercystéinémie chez un animal justifiant d'un tel traitement, ce traitement consistant en l'administration d'une dose pharmacologiquement efficace de thétine à l'animal concerné. L'invention, qui concerne en outre des compositions pharmaceutiques et nutritionnelles innovantes, concerne enfin un procédé permettant de réduire, voire de supprimer, la coûteuse supplémentation de l'alimentation protéinée du bétail en méthionine, choline et bétaïne.
Also published as
Latest bibliographic data on file with the International Bureau