Processing

Please wait...

Settings

Settings

Goto Application

1. WO1997029747 - METHODS FOR THE PREPARATION OF BIPHENYL ISOXAZOLE SULFONAMIDES

Publication Number WO/1997/029747
Publication Date 21.08.1997
International Application No. PCT/US1997/002917
International Filing Date 19.02.1997
Chapter 2 Demand Filed 16.09.1997
IPC
C07D 263/32 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
263Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
02not condensed with other rings
30having two or three double bonds between ring members or between ring members and non-ring members
32with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
C07D 405/12 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
405Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
CPC
A61P 9/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
12Antihypertensives
C07D 263/32
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
263Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
02not condensed with other rings
30having two or three double bonds between ring members or between ring members and non-ring members
32with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
C07D 405/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
405Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
Applicants
  • BRISTOL-MYERS SQUIBB COMPANY [US]/[US]
Inventors
  • POLNIASZEK, Richard, P.
  • WANG, Xuebao
  • DEPUE, Jeffrey, S.
  • PANDIT, Chennagiri, R.
  • GADAMASETTI, Kumar, G.
  • PENDRI, Yadagiri
  • MARTINEZ, Eduardo, J.
Agents
  • BABAJKO, Suzanne, E.
Priority Data
08/786,52321.01.1997US
60/001,97420.02.1996US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS FOR THE PREPARATION OF BIPHENYL ISOXAZOLE SULFONAMIDES
(FR) PROCEDES D'ELABORATION DE BIPHENYL ISOXAZOLE SULFAMIDES
Abstract
(EN)
Methods for the preparation of biphenyl isoxazole sulfonamides and intermediates thereof. The present invention also relates to the novel intermediates prepared by these methods. The biphenyl isoxazole sulfonamides prepared by the present methods are endothelin antagonists useful, $i(inter alia), for the treatment of hypertension.
(FR)
Procédés d'élaboration de biphényle isoxazole sulfamides et d'intermédiaires de ceux-ci. L'invention porte également sur de nouveaux intermédiaires obtenus par ces procédés. Les biphényles isoxazoles sulfamides obtenus selon ces procédés sont des antagonistes de l'endothéline utiles, notamment, pour le traitement de l'hypertension.
Latest bibliographic data on file with the International Bureau