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1. (WO1997029739) USE OF 5HT4 RECEPTOR ANTAGONISTS FOR OVERCOMING GASTROINTESTINAL EFFECTS OF SEROTONIN REUPTAKE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1997/029739 International Application No.: PCT/EP1997/000586
Publication Date: 21.08.1997 International Filing Date: 07.02.1997
Chapter 2 Demand Filed: 19.06.1997
IPC:
A61K 31/437 (2006.01) ,A61K 31/4453 (2006.01) ,A61K 31/454 (2006.01) ,A61K 31/46 (2006.01) ,A61K 45/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
4353
ortho- or peri-condensed with heterocyclic ring systems
437
the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
445
Non-condensed piperidines, e.g. piperocaine
4453
only substituted in position 1, e.g. propipocaine, diperodon
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
445
Non-condensed piperidines, e.g. piperocaine
4523
containing further heterocyclic ring systems
454
containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
46
8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Applicants:
MEULEMANS, Ann, Louise, Gabriëlle [BE/BE]; BE (UsOnly)
BOSMANS, Jean-Paul, René, Marie, André [BE/BE]; BE (UsOnly)
JANSSEN PHARMACEUTICA N.V. [BE/BE]; Turnhoutseweg 30 B-2340 Beerse, BE (AllExceptUS)
Inventors:
MEULEMANS, Ann, Louise, Gabriëlle; BE
BOSMANS, Jean-Paul, René, Marie, André; BE
Priority Data:
96200380.215.02.1996EP
Title (EN) USE OF 5HT4 RECEPTOR ANTAGONISTS FOR OVERCOMING GASTROINTESTINAL EFFECTS OF SEROTONIN REUPTAKE INHIBITORS
(FR) UTILISATION D'ANTAGONISTES DU RECEPTEUR DE 5HT4 POUR LUTTER CONTRE LES EFFETS GASTRO-INTESTINAUX D'INHIBITEURS DE REABSORPTION DE LA SEROTONINE
Abstract:
(EN) The present invention concerns the use of receptor antagonists of the 5HT4 receptor for avoiding, alleviating, suppressing or overcoming the gastrointestinal side-effects of serotonin reuptake inhibitors. The present invention also concerns pharmaceutical formulations comprising 5HT4 receptor antagonists for alleviating, suppressing or overcoming the gastrointestinal side-effects of serotonin reuptake inhibitors, as well as pharmaceutical compositions comprising 5HT4 receptor antagonists and serotonin reuptake inhibitors.
(FR) L'invention concerne l'utilisation d'antagonistes du récepteur de 5HT4 dans le but d'éviter, de soulager, de supprimer ou de surmonter les effets secondaires gastro-intestinaux d'inhibiteurs de réabsorption de la sérotonine. Elle concerne également des formulations pharmaceutiques comprenant des antagonistes du récepteur de 5HT4 dans le but de soulager, de supprimer ou de surmonter les effets secondaires gastro-intestinaux d'inhibiteurs de réabsorption de la sérotonine, ainsi que des compositions pharmaceutiques comprenant des antagonistes du récepteur de 5HT4 et des inhibiteurs de réabsorption de la sérotonine.
Designated States: AL, AM, AU, BA, BB, BG, BR, CA, CN, CU, CZ, EE, GE, HU, IL, IS, JP, KG, KR, LC, LK, LR, LT, LV, MD, MG, MK, MN, MX, NO, NZ, PL, RO, SG, SI, SK, TR, TT, UA, US, UZ, VN
African Regional Intellectual Property Organization (ARIPO) (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)