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1. WO1997027940 - SOLID PHASE SYNTHESIZER

Publication Number WO/1997/027940
Publication Date 07.08.1997
International Application No. PCT/US1996/020798
International Filing Date 26.12.1996
Chapter 2 Demand Filed 22.08.1997
IPC
B01J 19/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
C07K 1/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
1General processes for the preparation of peptides
04on carriers
CPC
B01J 19/0046
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
B01J 2219/00286
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
00277Apparatus
00279Features relating to reactor vessels
00281Individual reactor vessels
00286Reactor vessels with top and bottom openings
B01J 2219/00479
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
00277Apparatus
00479Means for mixing reactants or products in the reaction vessels
B01J 2219/00488
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
00277Apparatus
00479Means for mixing reactants or products in the reaction vessels
00488by rotation of the reaction vessels
B01J 2219/005
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
00277Apparatus
00497Features relating to the solid phase supports
005Beads
B01J 2219/00596
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
00583Features relative to the processes being carried out
00596Solid-phase processes
Applicants
  • CHUGAI PHARMACEUTICAL CO., LTD [JP]/[JP]
Inventors
  • EADIE, James, Scott
Agents
  • WARBURG, Richard, J.
  • MOON. Donald, Keith
Priority Data
08/593,63130.01.1996US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SOLID PHASE SYNTHESIZER
(FR) SYNTHETISEUR DE PHASE SOLIDE
Abstract
(EN)
Solid phase synthesizer and method of use for synthesis of a polymer. The synthesizer has a generally horizontal elongated vessel (10, 30) for holding a solid support and liquid having two ends (12, 14), each end having a porous blocker (16, 18, 32, 34) to prevent the solid support from leaving the vessel (10, 30) but allowing passage of the liquid from the vessel (10, 30). A particulate solid support is held within the vessel (10, 30) and has a size sufficient to prevent passage through the blocker (16, 18, 32, 34).
(FR)
Cette invention concerne un synthétiseur de phase solide ainsi que son procédé d'utilisation en vue de la synthèse d'un polymère. Ce synthétiseur comprend un récipient allongé et globalement horizontal (10, 30) qui renferme un support solide et un liquide. Ce récipient possède deux extrémités (12, 14) comportant chacune un obturateur poreux (16, 18, 32, 34) qui empêche le support solide de sortir du récipient (10, 30), mais permet au liquide de s'écouler hors de ce dernier (10, 30). Le récipient (10, 30) renferme un support solide particulaire d'une taille suffisante pour qu'il ne puisse passer à travers l'obturateur.
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