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1. WO1997026968 - THERAPEUTIC ANTI-ASTHMA AGENTS CONTAINING SELENIUM COMPOUNDS

Publication Number WO/1997/026968
Publication Date 31.07.1997
International Application No. PCT/DE1997/000135
International Filing Date 27.01.1997
Chapter 2 Demand Filed 01.08.1997
IPC
A61K 31/167 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
165having aromatic rings, e.g. colchicine, atenolol, progabide
167having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
A61K 31/41 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
CPC
A61K 31/167
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
165having aromatic rings, e.g. colchicine, atenolol, progabide
167having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
A61K 31/41
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
A61P 11/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
A61P 11/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
08Bronchodilators
Applicants
  • A. NATTERMANN & CIE. GMBH [DE]/[DE] (AllExceptUS)
  • UCHIDA, Yoshiyuki [JP]/[JP] (UsOnly)
  • AKASHI, Akira [JP]/[JP] (UsOnly)
Inventors
  • UCHIDA, Yoshiyuki
  • AKASHI, Akira
Agents
  • BEINES, Ulrich
Priority Data
8/1184826.01.1996JP
Publication Language German (DE)
Filing Language German (DE)
Designated States
Title
(DE) THERAPEUTISCHE MITTEL, ENTHALTEND ORGANISCHE SELENVERBINDUNGEN GENGEN ASTHMA
(EN) THERAPEUTIC ANTI-ASTHMA AGENTS CONTAINING SELENIUM COMPOUNDS
(FR) AGENTS THERAPEUTIQUES CONTENANT DES COMPOSES SELENIUM, AGISSANT CONTRE L'ASTHME
Abstract
(DE)
Es wird ein therapeutisches Mittel beschrieben, das als Wirkstoff eine Verbindung, die durch die nachfolgende Formel (1) und/oder (1') wiedergegeben ist, und/oder ein pharmazeutisch akzeptables Salz dieser Verbindung umfaßt. Das erfindungsgemäße Mittel zeigt hohe Wirksamkeiten sowohl in bezug auf die unmittelbaren als auch späten asthmatischen Reaktionen und insbesondere auf die späten asthmatischen Reaktionen. Bedingt durch die geringe Toxizität kann das erfindungsgemäße Mittel sicher beim Menschen dargereicht werden.
(EN)
The description relates to a therapeutic agent which comprises as the active agent a compound given by the formula (1) and/or (1') and/or a pharmaceutically acceptable salt thereof. The agent of the invention exhibits great effectiveness in cases of both immediate and later asthmatic reactions, especially the latter. Owing to its low toxicity, the agent of the invention can safely be prescribed for human beings.
(FR)
L'invention concerne un agent thérapeutique qui contient pour principe actif un composé représenté par la formule (1) et/ou la formule (1') et/ou un sel pharmaceutiquement acceptable dudit composé. Cet agent présente une grande efficacité aussi bien en cas de réaction asthmatique immédiate qu'en cas de réaction asthmatique tardives notamment dans ce dernier cas. Le faible degré de toxicité de cet agent lui permet d'être administré à l'homme en toute fiabilité.
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