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1. WO1997026331 - USE OF NEURONAL APOPTOSIS INHIBITOR PROTEIN (NAIP)

Publication Number WO/1997/026331
Publication Date 24.07.1997
International Application No. PCT/IB1997/000142
International Filing Date 17.01.1997
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 48/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
C07K 14/47 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
CPC
A01K 2217/05
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
2217Genetically modified animals
05Animals comprising random inserted nucleic acids (transgenic)
A01K 2227/105
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
2227Animals characterised by species
10Mammal
105Murine
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 48/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61P 31/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
Applicants
  • UNIVERSITY OF OTTAWA [CA]/[CA] (AllExceptUS)
  • KORNELUK, Robert, G. [CA]/[CA] (UsOnly)
  • MACKENZIE, Alexander, E. [CA]/[CA] (UsOnly)
  • ROY, Natalie [CA]/[CA] (UsOnly)
  • ROBERTSON, George [CA]/[CA] (UsOnly)
  • TAMAI, Katsu [JP]/[JP] (UsOnly)
Inventors
  • KORNELUK, Robert, G.
  • MACKENZIE, Alexander, E.
  • ROY, Natalie
  • ROBERTSON, George
  • TAMAI, Katsu
Agents
  • MORROW, Joy, D.
Priority Data
9601108.519.01.1996GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) USE OF NEURONAL APOPTOSIS INHIBITOR PROTEIN (NAIP)
(FR) UTILISATION DE LA PROTEINE INHIBITRICE D'APOPTOSE NEURONALE (NAIP)
Abstract
(EN)
The invention provides NAIP nucleic and sequences. Also provided are anti-NAIP antibodies and methods for modulating apoptosis and detecting compounds which modulate apoptosis.
(FR)
Cette invention concerne un acide nucléique de la protéine inhibitrice de l'apoptose neuronale (NAIP) ainsi que des séquences de cette protéine. Elle concerne également des anticorps dirigés contre ladite protéine NAIP ainsi que des procédés de modulation de l'apoptose et de sélection de composés qui modulent l'apoptose.
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