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1. WO1997025619 - DISPLACEMENT ASSAY ON A POROUS MEMBRANE

Publication Number WO/1997/025619
Publication Date 17.07.1997
International Application No. PCT/US1996/016981
International Filing Date 18.10.1996
Chapter 2 Demand Filed 18.10.1996
IPC
G01N 33/543 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
CPC
G01N 33/54386
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
54366Apparatus specially adapted for solid-phase testing
54386Analytical elements
Applicants
  • THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE NAVY [US]/[US]
Inventors
  • LIGLER, Frances, S.
  • KUSTERBECK, Anne, W.
  • RABBANY, Sina, Y.
Agents
  • McDONNELL, Thomas, E.
Priority Data
08/583,91211.01.1996US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DISPLACEMENT ASSAY ON A POROUS MEMBRANE
(FR) DOSAGE DU TYPE A DEPLACEMENT SUR MEMBRANE POREUSE
Abstract
(EN)
Displacement assays, under non-equilibrium conditions, are performed by flowing a liquid sample through a membrane (12) having binding elements with binding sites saturated with a labelled form of the analyte. Analyte in the sample displaces, under non-equilibrium conditions, the labelled form of the analyte from the membrane. The displaced labelled form of the analyte may then be detected.
(FR)
On procède à des dosages du type à déplacement dans des conditions de non équilibre en faisant passer un échantillon liquide par une membrane (12) présentant des éléments de fixation dans des sites de fixation saturés en formes marquées de l'analyte. L'analyte de l'échantillon déplace, dans des conditions de non équilibre, la forme marquée de l'analyte à partir de la membrane. Il devient alors possible de détecter les formes marquées de l'analyte.
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