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1. WO1997025039 - USE OF CARBONIC ANHYDRASE INHIBITORS (CAH) TO PREPARE A DRUG FOR CANCER THERAPY

Publication Number WO/1997/025039
Publication Date 17.07.1997
International Application No. PCT/EP1996/005793
International Filing Date 20.12.1996
IPC
A61K 31/166 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
165having aromatic rings, e.g. colchicine, atenolol, progabide
166having the carbon atom of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
A61K 31/433 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
433Thiadiazoles
CPC
A61K 31/166
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
165having aromatic rings, e.g. colchicine, atenolol, progabide
166having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
A61K 31/433
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
433Thidiazoles
A61K 31/4965
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
4965Non-condensed pyrazines
Applicants
  • HOECHST AKTIENGESELLSCHAFT [DE]/[DE] (AllExceptUS)
  • LANG, Hans, Jochen [DE]/[DE] (UsOnly)
  • GERICKE, Dietmar [DE]/[DE] (UsOnly)
Inventors
  • LANG, Hans, Jochen
  • GERICKE, Dietmar
Priority Data
196 00 721.612.01.1996DE
Publication Language German (DE)
Filing Language German (DE)
Designated States
Title
(DE) VERWENDUNG VON INHIBITOREN DES CARBOANHYDRATASE (CAH) ZUM HERSTELLEN EINES MEDIKAMENTS ZUR BEHANDLUNG VON KREBS
(EN) USE OF CARBONIC ANHYDRASE INHIBITORS (CAH) TO PREPARE A DRUG FOR CANCER THERAPY
(FR) UTILISATION D'INHIBITEURS DE L'ANHYDRASE CARBONIQUE (CAH) POUR PREPARER UN MEDICAMENT DESTINE AU TRAITEMENT DU CANCER
Abstract
(DE)
Beschrieben wird die Verwendung eines Carboanhydratase-Hemmers zur Herstellung eines Arzneimittels zur Behandlung von Tumoren, auch in Kombinationen mit einem in der Krebsbehandlung verwendeten Chemotherapeutikum, oder in Kombination mit einer physikalischen tumortherapeutischen Maßnahme; oder in Kombination mit einem Immunmodulator. Hervorragend geeignet ist Acetazolamid als Inhibitorkomponente der Carboanhydratase.
(EN)
The invention relates to the use of a carbonic anhydrase inhibitor to prepare a drug to treat tumours, also in associations with a chemotherapeutic agent used to treat cancer, or in association with physical tumour therapy, or in association with an immunomodulator. Acetazolamide is particularly suitable as a carbonic anhydrase inhibitor constituent.
(FR)
L'invention concerne l'utilisation d'un inhibiteur de l'anhydrase carbonique pour préparer un médicament destiné au traitement de tumeurs, également en associations avec un agent chimiothérapeutique employé dans le traitement du cancer, ou bien en association avec une physiothérapie antitumorale, ou encore en association avec un immunomodulateur. L'acétazolamide est éminemment approprié comme constituant inhibiteur de l'anhydrase carbonique.
Also published as
Latest bibliographic data on file with the International Bureau