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1. WO1997024601 - METHOD FOR TESTING A CELL SAMPLE

Publication Number WO/1997/024601
Publication Date 10.07.1997
International Application No. PCT/GB1996/003257
International Filing Date 27.12.1996
Chapter 2 Demand Filed 17.07.1997
IPC
G01N 15/12 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
10Investigating individual particles
12Coulter-counters
CPC
G01N 15/12
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
10Investigating individual particles
12Coulter-counters
G01N 2015/0073
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
0065biological, e.g. blood
0073Red blood cells
G01N 2015/105
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
10Investigating individual particles
105Other than optical measurement of deformation of individual particles
G01N 2015/1062
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
10Investigating individual particles
1062counting the particles by other than electro-optical means
G01N 2015/1087
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
10Investigating individual particles
1087Particle size
G01N 2015/1093
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
10Investigating individual particles
1093Particle shape
Applicants
  • SHINE, Thomas, Adam [GB]/[US]
  • SHINE, Ian, Basil [GB]/[US]
Inventors
  • SHINE, Thomas, Adam
  • SHINE, Ian, Basil
Agents
  • GILL JENNINGS & EVERY
Priority Data
9526649.029.12.1995GB
9526720.929.12.1995GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD FOR TESTING A CELL SAMPLE
(FR) PROCEDE POUR TESTER UN ECHANTILLON DE CELLULES
Abstract
(EN)
In this invention, a cell parameter, for example cell volume, is determined by subjecting one or more aliquots of a sample cell suspension to one or more alterations of at least one parameter of the cell environment to identify a point at which the cells achieve a particular shape to obtain a sample specific shape compensation factor. Preferably, the environmental parameter change is a reduction in osmolality.
(FR)
L'invention concerne la mesure d'un paramètre cellulaire, par exemple le volume cellulaire, que l'on obtient en soumettant une ou plusieurs aliquotes d'une suspension de cellules d'un échantillon à une ou plusieurs altérations d'au moins un paramètre de l'environnement des cellules étudiées, pour mettre en évidence un point où les cellules prennent une forme particulière afin d'obtenir un facteur de compensation de forme spécifique à l'échantillon. De préférence, le changement du paramètre de l'environnement est une réduction de l'osmolalité.
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