WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO1997022586) TRI-ARYL ETHANE DERIVATIVES AS PDE IV INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/022586    International Application No.:    PCT/CA1996/000839
Publication Date: 26.06.1997 International Filing Date: 11.12.1996
Chapter 2 Demand Filed:    11.07.1997    
IPC:
C07D 213/30 (2006.01)
Applicants: MERCK FROSST CANADA INC. [CA/CA]; 16711 Trans Canada Highway, Kirkland, Quebec H9H 3L1 (CA) (For All Designated States Except US).
GUAY, Daniel [CA/CA]; (CA) (For US Only).
GIRARD, Yves [CA/CA]; (CA) (For US Only).
DUCHARME, Yves [CA/CA]; (CA) (For US Only).
BLOUIN, Marc [CA/CA]; (CA) (For US Only).
HAMEL, Pierre [CA/CA]; (CA) (For US Only).
GIRARD, Mario [CA/CA]; (CA) (For US Only)
Inventors: GUAY, Daniel; (CA).
GIRARD, Yves; (CA).
DUCHARME, Yves; (CA).
BLOUIN, Marc; (CA).
HAMEL, Pierre; (CA).
GIRARD, Mario; (CA)
Agent: MURPHY, Kevin, P.; Swabey Ogilvy Renault, Suite 1600, 1981 McGill College, Montreal, Quebec H3A 2Y3 (CA)
Priority Data:
60/008,704 15.12.1995 US
9606377.1 26.03.1996 GB
Title (EN) TRI-ARYL ETHANE DERIVATIVES AS PDE IV INHIBITORS
(FR) DERIVES D'ETHANE TRI-ARYLE UTILISES COMME INHIBITEURS DE PDE IV
Abstract: front page image
(EN)The invention encompasses the novel compound of formula (I), useful in the treatment of diseases, including asthma, by raising the level of cyclic adenosine-3',5'-monophosphate (cAMP) through the inhibition of phosphodiesterase IV (PDE IV). The invention also encompasses certain pharmaceutical compositions and methods for treatment of diseases by inhibition of PDE IV, resulting in an elevation of cAMP, comprising the use of compounds of Formula (I).
(FR)Nouveau composé de formule (I) utilisé pour traiter des maladies, y compris l'asthme, par augmentation du niveau d'adénosine-3',5'-monophosphate cyclique (cAMP), cette augmentation étant obtenue par l'inhibition de la phosphodiestérase IV (PDE IV). L'invention se rapporte également à certaines compositions pharmaceutiques et à des méthodes de traitement des maladies par inhibition de la PDE IV, entraînant une augmentation de cAMP, ces méthodes consistant à utiliser des composés de la formule (I).
Designated States: AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CU, CZ, EE, GE, HU, IL, IS, JP, KG, KR, KZ, LC, LK, LR, LT, LV, MD, MG, MK, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, TJ, TM, TR, TT, UA, US, UZ, VN.
African Regional Intellectual Property Organization (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)