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Machine translation
1. (WO1997022333) ARCHAEOSOMES, ARCHAEOSOMES CONTAINING COENZYME Q¿10?, AND OTHER TYPES OF LIPOSOMES CONTAINING COENZYME Q¿10? AS ADJUVANTS AND AS DELIVERY VEHICLES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/022333    International Application No.:    PCT/CA1996/000835
Publication Date: 26.06.1997 International Filing Date: 13.12.1996
Chapter 2 Demand Filed:    03.07.1997    
IPC:
A61K 9/127 (2006.01), A61K 31/00 (2006.01), A61K 31/122 (2006.01), A61K 31/355 (2006.01), A61K 35/74 (2006.01), A61K 39/39 (2006.01), A61K 45/06 (2006.01)
Applicants: NATIONAL RESEARCH COUNCIL OF CANADA [CA/CA]; Intellectual Property Services Office, EG-12, Building M-58, Montreal Road, Ottawa, Ontario K1A 0R6 (CA) (For All Designated States Except US).
SPROTT, G., Dennis [CA/CA]; (CA) (For US Only).
PATEL, Girishchandra, B. [CA/CA]; (CA) (For US Only).
MAKABI-PANZU, Boby [CA/CA]; (CA) (For US Only).
TOLSON, Douglas, L. [CA/CA]; (CA) (For US Only)
Inventors: SPROTT, G., Dennis; (CA).
PATEL, Girishchandra, B.; (CA).
MAKABI-PANZU, Boby; (CA).
TOLSON, Douglas, L.; (CA)
Agent: ANDERSON, J., Wayne; National Research Council of Canada, Intellectual Property Services Office, EG-10, Building M-58, Montreal Road, Ottawa, Ontario K1A 0R6 (CA)
Priority Data:
60/008,724 15.12.1995 US
Title (EN) ARCHAEOSOMES, ARCHAEOSOMES CONTAINING COENZYME Q¿10?, AND OTHER TYPES OF LIPOSOMES CONTAINING COENZYME Q¿10? AS ADJUVANTS AND AS DELIVERY VEHICLES
(FR) ARCHEOSOMES, ARCHEOSOMES CONTENANT LA COENZYME Q¿10?, ET AUTRES TYPES DE LIPOSOMES CONTENANT LA COENZYME Q¿10? UTILISES COMME ADJUVANTS ET COMME VEHICULES D'APPORT
Abstract: front page image
(EN)The invention disclosure relates to novel archaesomes, and the use of archaesomes, for the enhanced delivery of pharmaceutical and other compounds to specific cell types and tissues in animals and other life-forms. The efficacy of the archaeosomes and of conventional liposomes can be further enhanced by incorporation of coenzyme Q¿10? and/or polyethylene glycol into the respective vesicles. Other coenzymes or vitamins, such as vitamin E, which have immunostimulatory properties may be included, or substituted for, CoQ¿10?. This invention also relates to the use of these vesicles in vaccine formulations, as adjuvants and/or delivery vehicles, for enhancing the immune response to immunogens in animals such as a human.
(FR)Nouveaux archéosomes et leur utilisation pour l'apport amélioré de produits pharmaceutiques et autres composés dans des tissus et des types de cellules spécifiques chez les animaux et d'autres types d'organismes vivants. L'efficacité de ces archéosomes et des liposomes classiques peut être davantage améliorée par l'incorporation de la coenzyme Q¿10? et/ou du polyéthylène glycol dans les vésicules respectives. D'autres coenzymes ou vitamines, telles que la vitamine E, qui possèdent des caractéristiques immunostimulatrices, peuvent être incluses, ou peuvent remplacer la CoQ¿10?. L'invention se rapporte également à l'utilisation de ces vésicules dans des formulations vaccinales, comme adjuvants et/ou comme véhicules d'apport, pour renforcer la réponse immune d'organismes tels que l'homme par rapport aux immunogènes.
Designated States: CA, JP, US.
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)