WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO1997021993) NUCLEAR RECEPTOR LIGANDS AND LIGAND BINDING DOMAINS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/021993    International Application No.:    PCT/US1996/020778
Publication Date: 19.06.1997 International Filing Date: 13.12.1996
Chapter 2 Demand Filed:    10.07.1997    
IPC:
C07K 1/00 (2006.01), C07K 14/72 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 22nd floor, 300 Lakeside Drive, Oakland, CA 94612-3550 (US)
Inventors: SCANLAN, Thomas, S.; (US).
BAXTER, John, D.; (US).
FLETTERICK, Robert, J.; (US).
WAGNER, Richard, L.; (US).
KUSHNER, Peter, J.; (US).
APRILETTI, James, L.; (US).
WEST, Brian, L.; (US).
SHIAU, Andrew, K.; (US)
Agent: NAKAMURA, Jackie, N.; Cooley Godward L.L.P., 3000 El Camino Real, Five Palo Alto Square, Palo Alto, CA 94306-2155 (US)
Priority Data:
60/008,540 13.12.1995 US
60/008,606 14.12.1995 US
Title (EN) NUCLEAR RECEPTOR LIGANDS AND LIGAND BINDING DOMAINS
(FR) LIGANDS DE RECEPTEURS NUCLEAIRES ET DOMAINES DE LIAISON DE LIGANDS
Abstract: front page image
(EN)The present invention provides new methods, particularly computational methods, and compositions for the generation of nuclear receptor synthetic ligands based on the three-dimensional structure of nuclear receptors, particularly the thyroid receptor (herein referred to as 'TR'). Also provided are crystals, nuclear receptor synthetic ligands, and related methods.
(FR)L'invention concerne des méthodes nouvelles, plus particulièrement des méthodes de calcul et des compositions pour la production de ligands synthétiques de récepteurs nucléaires sur la base de la structure tridimensionnelle de récepteurs nucléaires, en particulier le récepteur des hormones thyroïdiennes (appelé ici TR). Elle porte aussi sur des cristaux, des ligands synthétiques de récepteurs nucléaires et les méthodes associées.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, UZ, VN.
African Regional Intellectual Property Organization (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)