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Machine translation
1. (WO1997020925) MODIFIED VEGF ANTISENSE OLIGONUCLEOTIDES FOR TREATMENT OF SKIN DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/020925    International Application No.:    PCT/US1996/020441
Publication Date: 12.06.1997 International Filing Date: 06.12.1996
Chapter 2 Demand Filed:    30.06.1997    
IPC:
A61K 38/00 (2006.01), C12N 15/11 (2006.01)
Applicants: HYBRIDON, INC. [US/US]; 620 Memorial Drive, Cambridge, MA 02139 (US)
Inventors: SMYTH, Adrienne, P.; (US).
ROBINSON, Gregory, S.; (US)
Agent: KERNER, Ann-Louise; Hale and Dorr, Sixty State Street, Boston, MA 02109 (US)
Priority Data:
08/569,926 08.12.1995 US
08/629,730 09.04.1996 US
Title (EN) MODIFIED VEGF ANTISENSE OLIGONUCLEOTIDES FOR TREATMENT OF SKIN DISORDERS
(FR) OLIGONUCLEOTIDES ANTISENS SPECIFIQUES DU VEGF, MODIFIES, DESTINES AU TRAITEMENT DES TROUBLES CUTANES
Abstract: front page image
(EN)Disclosed are oligonucleotides complementary to VEGF-specific nucleic acid useful in reducing the expression of VEGF. Also disclosed are pharmaceutical formulations containing such oligonucleotides useful for treating various disorders associated with neovascularization and angiogenesis, and methods for treating psoriasis.
(FR)L'invention concerne des oligonucléotides complémentaires d'un acide nucléique spécifique du facteur de croissance endothélial vasculaire (VEGF), utiles pour diminuer l'expression de ce dernier. Elle concerne également des formulations pharmaceutiques contenant lesdits oligonucléotides, utiles pour le traitement de divers troubles associés à une néovascularisation et à une angiogénèse, ainsi que des méthodes de traitement du psoriasis.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, FI, GB, GE, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, UZ, VN.
African Regional Intellectual Property Organization (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)