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Machine translation
1. (WO1997020218) CALCIUM CHANNEL MODULATOR COMPOSITIONS AND METHODS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/020218    International Application No.:    PCT/US1996/019002
Publication Date: 05.06.1997 International Filing Date: 27.11.1996
Chapter 2 Demand Filed:    18.06.1997    
IPC:
A61K 38/00 (2006.01), C07K 14/705 (2006.01), G01N 33/68 (2006.01)
Applicants: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY [US/US]; Stanford, CA 94305 (US)
Inventors: TSIEN, Richard, W.; (US).
BEZPROZVANNY, Ilya; (US).
SCHELLER, Richard, H.; (US)
Agent: SHOLTZ, Charles, K.; Dehlinger & Associates, P.O. Box 60850, Palo Alto, CA 94306-0850 (US)
Priority Data:
60/008,257 01.12.1995 US
Title (EN) CALCIUM CHANNEL MODULATOR COMPOSITIONS AND METHODS
(FR) COMPOSITIONS MODULATRICES DES CANAUX CALCIQUES ET PROCEDES ASSOCIES
Abstract: front page image
(EN)A syntaxin-derived composition containing a peptide capable of shifting the steady-state inactivation curve of a voltage-dependent calcium ion channel in the hyperpolarized direction, a method of selectively inhibiting the opening of voltage-dependent calcium ion channels associated with neurotransmitter release, and screening method of identifying a compound capable of modulating the opening of voltage-dependent calcium ion channels.
(FR)Composition dérivée de la syntaxine, contenant un peptide capable de déplacer dans le sens de l'hyperpolarisation la courbe d'inactivation à l'équilibre d'un canal calcique potentiel-dépendant, procédé permettant d'inhiber sélectivement l'ouverture des canaux calciques potentiel-dépendants associés à la libération de neurotransmetteurs, et procédé permettant d'identifier un composé capable de moduler l'ouverture desdits canaux.
Designated States: AU, CA, JP.
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)