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Machine translation
1. (WO1997020075) SCREENING ASSAY FOR COMPOUNDS STIMULATING SOMATOSTATIN AND INSULIN PRODUCTION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/020075    International Application No.:    PCT/US1996/019009
Publication Date: 05.06.1997 International Filing Date: 27.11.1996
Chapter 2 Demand Filed:    27.05.1997    
IPC:
C12Q 1/68 (2006.01), G01N 33/53 (2006.01)
Applicants: RESEARCH DEVELOPMENT FOUNDATION [US/US]; 402 North Division Street, Carson City, NV 89703 (US)
Inventors: MONTMINY, Marc, R.; (US).
PEERS, Bernard; (BE)
Agent: WEILER, James, F.; Suite 1560, 1 Riverway, Houston, TX 77056 (US)
Priority Data:
60/007,722 30.11.1995 US
Title (EN) SCREENING ASSAY FOR COMPOUNDS STIMULATING SOMATOSTATIN AND INSULIN PRODUCTION
(FR) CRIBLAGE POUR LA RECHERCHE DE COMPOSES STIMULANT LA PRODUCTION DE SOMATOSTATINE ET D'INSULINE
Abstract: front page image
(EN)The present invention provides a method to design compounds that mimic the effects of Pbx in stabilizing STF-1 binding. Using well-known DNA binding assays, a person having ordinary skill in this art would be able to screen compounds to determine drugs effective in promoting STF-1 binding to DNA. In this way, one will be able to discover new compounds useful in stimulating somatostatin and insulin production.
(FR)L'invention concerne un procédé permettant de mettre au point des composés mimant l'action de la Pbx dans la stabilisation de la liaison de la STF-1. Par des méthodes de criblage bien connues de la liaison de l'ADN, une personne expérimentée peut cribler des composés afin de déterminer les médicaments favorisant la fixation de la STF-1 sur l'ADN. Ceci permet de découvrir de nouveaux composés utiles pour stimuler la production de somatostatine et d'insuline.
Designated States: AM, AT, AU, BB, BG, BR, BY, CA, CH, CN, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LK, LR, LT, LU, LV, MD, MG, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TT, UA, UG, UZ, VN.
African Regional Intellectual Property Organization (KE, LS, MW, SD, SZ, UG)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)