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Machine translation
1. (WO1997019677) SUSTAINED-RELEASE DRUG DELIVERY SYSTEM
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/019677    International Application No.:    PCT/US1995/015587
Publication Date: 05.06.1997 International Filing Date: 30.11.1995
Chapter 2 Demand Filed:    16.05.1997    
IPC:
A61K 9/20 (2006.01), A61K 31/137 (2006.01)
Applicants: PHARMAVENE, INC. [US/US]; 1550 East Aude Drive, Rockville, MD 20850 (US)
Inventors: RUDNIC, Edward, M.; (US).
McCARTY, John, A.; (US).
BELENDUIK, George, W.; (US)
Agent: HERRON, Charles, J.; Carella, Byrne, Bain, Gilfillan, Cecchi, Stewart & Olstein, 6 Becker Farm Road, Roseland, NJ 07068 (US)
Priority Data:
Title (EN) SUSTAINED-RELEASE DRUG DELIVERY SYSTEM
(FR) SYSTEME D'ADMINISTRATION DE MEDICAMENT A LIBERATION PROLONGEE
Abstract: front page image
(EN)A sustained-release pharmaceutical composition comprising a highly soluble pharmaceutical agent, such as selegiline, in a pharmaceutical carrier comprising a hydrophilic polymer dispersed in a hydrophobic matrix. A hydrophilic microenvironment is created in a hydrophobic matrix by incorporating hydrophilic polymers within a hydrophobic matrix. Optionally, a binder, preferably a polyhydroyxlated compound, can also be added.
(FR)Composition pharmaceutique à libération prolongée comprenant un agent pharmaceutique hautement soluble tel que la sélégiline, dans un excipient pharmaceutique comprenant un polymère hydrophile dispersé dans une matrice hydrophobe. Un microenvironnement hydrophile est créé dans une matrice hydrophobe par incorporation de polymères hydrophiles à l'intérieur d'une matrice hydrophobe. On peut également ajouter, à titre d'option, un liant, de préférence un composé polyhydroxylé.
Designated States: AU, CA, JP, MX.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)