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1. (WO1997019106) COLLAGEN-LIKE PEPTOID RESIDUE-CONTAINING STRUCTURES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1997/019106 International Application No.: PCT/US1996/018521
Publication Date: 29.05.1997 International Filing Date: 18.11.1996
Chapter 2 Demand Filed: 21.05.1997
IPC:
C07K 5/083 (2006.01) ,C07K 7/06 (2006.01) ,C07K 7/08 (2006.01) ,C07K 14/00 (2006.01) ,C07K 14/78 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
5
Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
04
containing only normal peptide links
08
Tripeptides
083
the side chain of the first amino acid being acyclic, e.g. Gly, Ala
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
06
having 5 to 11 amino acids
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
08
having 12 to 20 amino acids
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
78
Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin (CIG)
Applicants:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 22nd floor 300 Lakeside Drive Oakland, CA 94612-3550, US
Inventors:
GOODMAN, Murray; US
TAULANE, Joseph, P.; US
FENG, Yangbo; US
MELACINI, Giuseppe; US
Agent:
SIMPSON, Andrew, H.; Knobbe, Martens, Olson and Bear 16th floor 620 Newport Center Drive Newport Beach, CA 92660, US
Priority Data:
08/668,38021.06.1996US
60/006,89417.11.1995US
Title (EN) COLLAGEN-LIKE PEPTOID RESIDUE-CONTAINING STRUCTURES
(FR) STRUCTURES CONTENANT DES RESIDUS PEPTOIDES DE TYPE COLLAGENE
Abstract:
(EN) Synthetic collagen in triple helical conformation and comprising amino acid chains of repeating trimers of highly populated collagen sequences as well as those sequences wherein the proline or hydroxyproline residue is replaced with a peptoid residue. The invention includes methods of preparing synthetic collagen structures having the triple helix conformation present in collagen from collagen-type polypeptides and poly(peptide-peptoid residue) chains by means of a helix-inducing template.
(FR) L'invention se rapporte à un collagène synthétique de conformation en triple hélice qui comprend des chaînes d'acides aminés de trimères récurrents constitués de séquences collagéniques fortement peuplées, et également constitué de ces séquences dans lesquelles le résidu de proline ou d'hydroxyproline est remplacé par un résidu peptoïde. L'invention se rapporte à des procédés de préparation de structures collagéniques synthétiques présentant la conformation en triple hélice présente dans le collagène, à partir de polypeptides de type collagène et de chaînes de résidus poly(peptide-peptoïdes) au moyen d'une matrice induisant une hélice.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, UZ, VN
African Regional Intellectual Property Organization (ARIPO) (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0861264JP2000500497 CA2237845AU1997010549