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1. (WO1997019080) NOVEL INTERMEDIATES AND THEIR USE TO PREPARE N,N'-BRIDGED BISINDOLYLMALEIMIDES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1997/019080 International Application No.: PCT/US1996/018518
Publication Date: 29.05.1997 International Filing Date: 18.11.1996
Chapter 2 Demand Filed: 18.06.1997
IPC:
C07D 498/22 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
498
Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
22
in which the condensed system contains four or more hetero rings
Applicants:
ELI LILLY AND COMPANY [US/US]; Lilly Corporate Center Indianapolis, IN 46285, US (AllExceptUS)
FAUL, Margaret, M. [IE/US]; US (UsOnly)
KRUMRICH, Christine, A. [US/US]; US (UsOnly)
WINNEROSKI, Leonard, L., Jr. [US/US]; US (UsOnly)
Inventors:
FAUL, Margaret, M.; US
KRUMRICH, Christine, A.; US
WINNEROSKI, Leonard, L., Jr.; US
Agent:
CALTRIDER, Steven, P. ; Eli Lilly and Company Lilly Corporate Center Indianapolis, IN 46285, US
Priority Data:
60/007,34520.11.1995US
Title (EN) NOVEL INTERMEDIATES AND THEIR USE TO PREPARE N,N'-BRIDGED BISINDOLYLMALEIMIDES
(FR) NOUVEAUX INTERMEDIAIRES ET LEUR UTILISATION POUR LA PREPARATION DES BISINDOLYLMALEIMIDES PONTES EN N,N'
Abstract:
(EN) This invention provides compounds of formula (II). The invention further provides the use of this compound to prepare N,N'-bridged bisindolylmaleimides. Furthermore, the invention provides pharmaceutical formulations and the methods of use for inhibiting Protein Kinase C in mammals.
(FR) L'invention concerne des composés présentant la formule (II). En outre, l'invention prévoit l'utilisation de ce composé dans la préparation des bisindolylmaléimides pontés en N, N'. De plus, l'invention traite de formulations pharmaceutiques et des procédés d'utilisation pour inhiber la protéine kinase C chez le mammifère.
Designated States: AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CU, CZ, EE, GE, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, RO, RU, SD, SG, SI, SK, TJ, TM, TR, TT, UA, UG, US, UZ, VN
African Regional Intellectual Property Organization (ARIPO) (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
CZPV1998-1503NO19982105TR1998/00876MXPA/a/1998/003791SG53621IL124415
JP2008138006JP2000500496 AR04718CN1207740CA2237401EA199800368
KR1019990067600NZ323282AU1996077388MYPI 96004798IN1999/CAL/1996